Urologic disorders in infants and children

Author(s): Elder JS


Background: Assessment of the antimicrobial sensitivity pattern in urinary isolates of the children suffering from urinary tract infection (UTI) and evaluation of the recent trends of multi-drug resistance in the isolates. The aim was to find out the antibiotics sensitivity of the organisms isolated from the urine samples of pediatric age-group with emphasis on their resistance pattern.

Methods: A clinico-epidemiological study comprising of 304 specimens of urine were collected among all the children with UTI below 12 years of age, attending pediatric outpatient department of a tertiary care teaching hospital in eastern India wet mount microscopy and semi quantitative culture were done to diagnose UTI. Organisms isolated were identified by standard biochemical tests, and antibiogram studies were done by standard Kirby-Bauer disc diffusion test statistical analysis, Microsoft excel and SPSS were used for analysis of data.

Results: Aminoglycosides had wider sensitivity pattern toward most of the uropathogens whereas tetracyclines and co-amoxyclav in particular were resistant for most of the organisms. Among all the organisms, Pseudomonas and Enterococcus species showed higher resistance pattern toward the conventional antimicrobials.

Conclusions: The changing trends in the anti-biograms of several Gram-positive and Gram-negative microorganisms in UTI demands reconsideration with respect to rational drug use in the pediatric age group.

Similar Articles

Prevalence of urinary tract infection in childhood: A meta-analysis

Author(s): Shaikh N, Morone NE, Bost JE, Farrell MH

The changing epidemiology of serious bacterial infections in young infants

Author(s): Greenhow TL, Hung YY, Herz AM, Losada E, Pantell RH

Prevalence of urinary tract infection in childhood: A meta-analysis

Author(s): Sheikh N, Morone NE, Bost JE, Farerell MH

Does this child have urinary tract infection? JAMA 298:  2895-2904

Author(s): Shaikh N, Morone NE, Lopez J, Chianese J, Sangvai S, et al.

  Improving antibiotic prescribing for pediatric urinary tract infections in outpatient settings

Author(s): Matthew F. Daley, Sharisse M, Arnold R, Karen A, Glenn Liza M, et al.

The importance of gender stratified antibiotic resistance surveillance study

Author(s): den Heijer CD, Penders J, Donker GA, Bruggeman CA Bruggeman CA, et al.

Antibiotic resistance patterns of outpatient pediatric urinary tract infections

Author(s): Edlin RS, Shapiro DJ, Hersh AL, Copper HL