Author(s): Woodruff-Pak DS, Lavond DG, Logan CG, Steinmetz JE, Thompson RF
Portions of cerebellar cortex, particularly Larsell's hemisphere VI, have been identified as involved but not essential for the acquisition and retention of classical conditioning of the nictitating membrane (NM) response in rabbit. The present experiment was undertaken to examine the effect of lesions of cerebellar cortical regions projecting to anterior dorsolateral interpositus nucleus. Lesions of relatively equal size, including hemisphere VI and additionally more medial, anterior, or lateral cerebellar cortex were made after rabbits were classically conditioned. The effect of these cerebellar cortical lesions on retention to tone versus light conditioned stimulus (CS) and the timing of the conditioned response was evaluated. In spite of relatively large cerebellar cortical lesions, reacquisition of the conditioned NM response occurred quite rapidly. Whether the lesion was more medial and anterior or more lateral did not affect retention. Retention was significantly poorer with light CS than with tone CS. Timing of CRs was not affected by these lesions of cerebellar cortex, but the lesions spared most of the anterior lobe. The parasagittal zone C3 covering the longitudinal band of tissue from anterior lobe to the paramedian lobule and projecting to dorsolateral anterior interpositus requires additional exploration for its role in classical NM conditioning.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/8495350
Author(s): Lu X, Miyachi S, Ito Y, Nambu A, Takada M
Author(s): Lu X, Miyachi S, Takada M
Author(s): McCormick DA, Thompson RF
Author(s): Gerwig M, Haerter K, Hajjar K, Dimitrova A, Maschke M, et al.
Author(s): Logan CG, Grafton ST
Author(s): Blaxton TA, Zeffiro TA, Gabrieli JD, Bookheimer SY, Carrillo MC, et al.
Author(s): Schreurs BG, McIntosh AR, Bahro M, Herscovitch P, Sunderland T, et al.
Author(s): Molchan SE, Sunderland T, McIntosh AR, Herscovitch P, Schreurs BG
Author(s): Lu X, Hikosaka O, Miyachi S
Author(s): Gruart A , Guillazo-Blanch G, Fernandez-Mas R, Jimenez-Diaz L, Delgado-Garcia JM
Author(s): Park JS, Onodera T, Nishimura S, Thompson RF, Itohara S
Author(s): Lavond DG, Hembree TL, Thompson RF
Author(s): Skelton RW
Author(s): Steinmetz JE, Lavond DG, Ivkovich D, Logan CG, Thompson RF
Author(s): Swain RA, Shinkman PG, Thompson JK, Grethe JS, Thompson RF
Author(s): Chapman PF, Steinmetz JE, Sears LL, Thompson RF
Author(s): Bao S, Chen L, Kim JJ, Thompson RF
Author(s): Kleim JA, Freeman JH Jr, Bruneau R, Nolan BC, Cooper NR, et al.
Author(s): Miller MJ, Chen NK, Li L, Tom B, Weiss C, et al.
Author(s): Hikosaka O, Nakahara H, Rand MK, Lu X, Nakamura K, et al.
Author(s): Lu X, Ashe J
Author(s): Ashe J, Lungu OV, Basford, AT, Lu X
Author(s): Nawrot M, Rizzo M
Author(s): Nawrot M, Rizzo M
Author(s): Schmahmann JD, Sherman JC.
Author(s): Thier P, Haarmeier T, Treue S, Barash S
Author(s): Jokisch D, Troje NF, Koch B, Schwarz M, Daum I
Author(s): Maschke M, Gomez CM, Tuite PJ, Pickett K, Konczak J
Author(s): Ravizza SM, McCormick CA, Schlerf JE, Justus T, Ivry RB, et al.
Author(s): Haarmeier T, Thier P
Author(s): Richter S, Gerwig M, Aslan B, Wilhelm H, Schoch B, et al.
Author(s): Ritvo ER, Freeman BJ, Scheibel AB, Duong T, Robinson H, et al.