Author(s): Benaim C, Desnuelle C, Fourniere-Mehouas M
There is a need of standardized and quantitative clinical assessments of ALS patients receiving new treatments. Some clinical scales, that are based on patients interviews and/or on physical examination, allow to quantify the patient functional status over time. The ALSFRS has been validated for that purpose and is one the most commonly used scales in clinical trials. Its revised version (the ALSFRS-R) has recently shown excellent metric properties. Functional scales are part of the clinical evaluation of ALS patients, and complete the quantitative assessment of muscle strength, that includes the Manual Muscular Testing (MMT) and the Maximal Voluntary Isometric Contraction (MVIC). Readers will find in this article a (non-exhaustive) listing of functional and motor scales that can be useful both in clinical trials of experimental agents and in daily practice.
Referred From: https://www.researchgate.net/publication/6670427_Functional_scales_and_motor_assessment_in_ALS
Author(s): Lattante S, Conte A, Zollino M, Luigetti M, Del Grande A, et al.
Author(s): Sedda A
Author(s): Strong MJ, Abrahams S, Goldstein LH, Wooley S, Mclaughlin P, et al.
Author(s): Chiò A, Battistini S, Calvo A, Caponnetto C, Conforti FL, et al.
Author(s): Sabatelli M, Marangi G, Conte A, Tasca G, Zollino M, et al.
Author(s): Lattante S, Pomponi MG, Conte A, Marangi G, Bisogni G, et al.
Author(s): McCullagh S, Moore M, Gawel M, Feinstein A
Author(s): Agosta F, Al-Chalabi A, Filippi M, Hairdman O, Kaji R, et al.
Author(s): Murphy J, Ahmed F, Lomen-Hoert C
Author(s): Pagnini F, Zachary S (Ed)
Author(s): Goldstein LH, Abrahams S
Author(s): Elamin M, Bede P, Byrne S, Jordan N, Gallagher L, et al.
Author(s): Robinson KM, Lacey SC, Grugan P, Glosser G, Grossman M, et al.
Author(s): Kim SM, Lee KM, Jong YH, Park KS, Yang JH, et al.
Author(s): Grossman AB, Bonnie EL, Bradley WG
Author(s): Lulè D, Paulì S, Altinas E, Singer U, Mèrk T, et al.
Author(s): Brown WA, Mueller PS
Author(s): Houpt JL, Gould BS, Norris FHJr
Author(s): Peters PK, Swenson WM, Mulder DW
Author(s): Poletti B, Carelli L, Lafronza A, Solca F, Faini A, et al.
Author(s): McElhiney MC, Rabkin JC, Gordon PH, Goetz R, Mitsumoto H
Author(s): Talbot K, Ansorge O
Author(s): Girardi A, MacPherson SE, Abrahams S
Author(s): Lillo P, Savage S, Mioshui E, Kiernan MC, Hodges JR
Author(s): Frances A
Author(s): Beeldman E, Raaphorst J, Klein Twennaar M, de Visser M, Schmand BA, et al.
Author(s): Trojsi F, Siciliano M, Femiano C, Santangelo G, Lunetta C, et al.
Author(s): ALS CNTF Treatment Study (ACTS) Phase I-II Study Group
Author(s): Cedarbaum JM, Stambler N
Author(s): Poletti B, Solca F, Carelli L, Madotto F, Lafronza A, et al.
Author(s): Strong MJ, Grace GM, Freedman M, Lomen-Hoerth C, Woolley S, et al.
