Frail elderly, nutritional status and drugs

Author(s): Pickering G

Abstract

This review focuses on the interactions between nutritional status and drugs in frail elderly persons. Impairment of nutritional status, a component of clinical presentation in the frail elderly, has a major impact on the pharmacology of many drugs devolving from the physiological alterations it generates. Food itself plays a central role in nutritional status and in possible interactions with drugs. Conversely, drugs have often, directly and indirectly, a deleterious effect on the nutritional state of the elderly. However, research in this domain is scarce, and future clinical studies will need to include more elderly and frail elderly individuals, to help clinicians to better understand these interactions.

Similar Articles

Barriers to nutrition care for nursing home residents

Author(s): Crogan NL, Shultz JA, Adams CE, Massey LK

Upper gastrointestinal pH in seventy-nine healthy, elderly, North American men and women

Author(s): Russell TL, Berardi RR, Barnett JL, Dermentzoglou LC, Jarvenpaa KM, et al.

Enhanced oral cyclosporine absorption with water-soluble vitamin E early after liver transplantation

Author(s): Pan SH, Lopez RR Jr, Sher LS, Hoffman AL, Podesta LG, et al.

Enhancement of the bioavailability of propranolol and metoprolol by food

Author(s): Melander A, Danielson K, Scherstén B, Wåhlin E

Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey

Author(s): Kaufman DW, Kelly JP, Rosenberg L, Anderson TE, Mitchell AA

Intake of medication and vitamin status in the elderly

Author(s): Fabian E, Bogner M, Kickinger A, Wagner KH, Elmadfa I

Risk of malnutrition in retirement homes elderly persons measured by the "mini-nutritional assessment"

Author(s): Griep MI, Mets TF, Collys K, Ponjaert-Kristoffersen I, Massart DL

Taste loss in hospitalized multimorbid elderly subjects

Author(s): Toffanello ED, Inelmen EM, Imoscopi A, Perissinotto E, Coin A, et al.

Use of proton-pump inhibitors and their associated risks among frail elderly nursing home residents

Author(s): Teramura-Grönblad M, Hosia-Randell H, Muurinen S, Pitkala K

Bacterial overgrowth without clinical malabsorption in elderly hypochlorhydric subjects

Author(s): Saltzman JR, Kowdley KV, Pedrosa MC, Sepe T, Golner B, et al.

Food-drug interactions

Author(s): Schmidt LE, Dalhoff K