Author(s): Iglehart IW 3rd, Sutton JD, Bender JC, Shaw RA, Ziminski CM, et al.
This prospective, double blind study was undertaken to test the efficacy of intravenous "minipulse" (100 mg) methylprednisolone (MP) therapy versus standard pulse (1000 mg) MP therapy in rheumatoid arthritis (RA). Thirty-six patients with RA synovitis flares were randomized to receive either 100 or 1000 mg MP IV QD x 3 doses. These 2 universally comparable groups exhibited no statistically significant differences in their striking prompt and sustained clinical improvement. These data suggest that minipulse MP is as efficacious as conventional pulse MP in the treatment of RA flares.
Referred From: https://pubmed.ncbi.nlm.nih.gov/2319516/
Author(s): Kimberly RP
Author(s): Ejstrup L, Peters ND
Author(s): Peters ND, Ejstrup L
Author(s): Malaviya AN, Kapoor S, Garg S, Ahmad I, Raja RR
Author(s): Gaydukova IZ, Rebrov AP, Poddubnyi DA
Author(s): van der Linden S, Valkenburg HA, Cats A
Author(s): Nasswetter G, Piñeiro DJ, Garcia Morteo OM, Maldonado Cocco JA, Barreira JC, et al.