Formulationfor controlled release of drugs by combining hydrophilic and hydrophobicagents

Author(s): Kochinke F, Wong V

Abstract

Combinations of hydrophilic and hydrophobic entities in a biodegradable sustained release implant are shown to modulate each other's rate of release. Formulations of a therapeutically active agent and modulator provide substantially constant rate of release for an extended period of time.

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