Recommended Conferences

Cancer-Treatment and Therapeutics

New York, USA
Related Subjects
 

The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation

Author(s): Cervelli V, Garcovich S, Bielli A, Cervelli G, Curcio BC, et al.

Abstract

To investigate the safety and clinical efficacy of AA-PRP injections for pattern hair loss. AA-PRP, prepared from a small volume of blood, was injected on half of the selected patients’ scalps with pattern hair loss. The other half was treated with placebo. Three treatments were given for each patient, with intervals of 1 month. The endpoints were hair re-growth, hair dystrophy as measured by dermoscopy, burning or itching sensation, and cell proliferation as measured by Ki-67 evaluation. At the end of the 3 cycles of treatment, the patients presented clinical improvement in the mean number of hairs, with a mean increase of 18.0 hairs in the target area, and a mean increase in total hair density of 27.7 ( number of hairs/cm2) compared with baseline values. Microscopic evaluation showed the increase of epidermis thickness and of the number of hair follicles two weeks after the last AA-PRP treatment compared to baseline value (). We also observed an increase of Ki67+ keratinocytes of epidermis and of hair follicular bulge cells and a slight increase of small blood vessels around hair follicles in the treated skin compared to baseline ().

Similar Articles

Clinical utility and validity of minoxidil response testing in androgenetic alopecia

Author(s): Goren A, Shapiro J, Roberts J, McCoy J, Desai N, et al.

Androgenetic alopecia: an update

Author(s): Kaliyadan F, Nambiar A, Vijayaraghavan S

Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

Author(s): Cervantes J, Perper M, Wong L, Eber A, Villasante A, et al.

Hair follicle growth by stromal vascular fraction-enhanced adipose transplantation in baldness

Author(s): Perez-Meza D, Ziering C, Sforza M, Krishnan G, Ball E, et al.

Classification of Male-pattern Hair Loss

Author(s): Wirya CT, Wu W, Wu K

Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling

Author(s): Festa E, Fretz J, Berry R, Schmidt B, Rodeheffer M, et al.

The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study

Author(s): Anitua E, Pino A, Martinez N, Orive G, Berridi D

The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

Author(s): Gentile P, Garcovich S, Bielli A, Scioli MG, Orlandi A, et al.

Study of platelet-rich plasma injections in the treatment of androgenetic alopecia through an one-year period

Author(s): Gkini MA, Kouskoukis AE, Tripsianis G, Rigopoulos D, Kouskoukis K

Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia

Author(s): Ibrahim ZA, Elmaadawi IH, Mohamed BM, Abdou SM, El Attar YA, et al.