Author(s): Jahns AC, Alexeyev OA
Propionibacterium acnes is regarded as a common member of the human skin microbiota, often occurring in biofilms. Little is known about the size of bacterial biofilms in hair follicles as a few sections of biopsy tissue are routinely evaluated. Transversal sectioning provides a better opportunity for histological analyses of hair follicles which can be followed through the different morphological levels. Direct visualization of P. acnes biofilms in hundreds of consecutive sections allowed insight into the 3D distribution in human hair follicles as well as investigating the depth of biofilm distribution within hair follicles. Four distinct colonization patterns of P. acnes biofilms were revealed. Results have shown that an individual P. acnes biofilm can spread for 1900 μm in a terminal hair follicle. This information can be of help while designing potential antibiofilm treatment.
Referred From: https://onlinelibrary.wiley.com/doi/10.1111/exd.12482
Author(s): Collier CN, Harper JC, Cafardi JA, Cantrell WC, Wang W, et al.
Author(s): McDowell A, Perry AL, Lambert PA, Patrick S
Author(s): Coates A, Hu Y, Bax R, Page C
Author(s): Holmberg A, Lood R, Mörgelin M
Author(s): Tyner H, Patel R
Author(s): Coenye T, Peeters E, Nelis HJ
Author(s): Burkhart CG, Burkhart CN
Author(s): Bruggeman H, Henne A, Hoster F
Author(s): Jahns AC, Lundskog B, Ganceviciene R
Author(s): Burkhart CG, Butcher C, Burkhart CN, Lehmann PF
Author(s): Nagy I, Pivarcsi A, Koreck A, Széll M, Urbán E, et al.
Author(s): Tukel C, Wilson RP, Nishimori JH, Pezeshki M, Chromy BA, et al.
Author(s): Biragyn A, Ruffini PA, Leifer CA, Klyushnenkova E, Shakhov A, et al.
Author(s): Kawai T, Akira S
Author(s): Lwin SM, Kimber I, Mcfadden JP
Author(s): Sivasankar C, Maruthupandiyan S, Balamurugan K, James PB, Krishnan V, et al.
Author(s): Coenye T, Brackman G, Rigole P
Author(s): Feuillolay C, Pecastaings S, Le gac C, Fiorini-Puybaret C, Luc J, et al.
Author(s): Allen HB, Hossain C, Abidi N, Larijani M, Joshi SG
Author(s): Brackman G, Forier K, Al quntar AA, De Canck E, Enk CD, et al.