Comparisons of short- and intermediate-term effects of pitavastatin versus atorvastatin on lipid profiles, fibrinolytic parameter, and endothelial function

Author(s): Sakabe K, Fukuda N, Fukuda Y, Wakayama K, Nada T, et al.


We compared short- and intermediate-term effects on lipid profiles, fibrinolytic parameter, and endothelial function between pitavastatin and atorvastatin. Short-term improvement of endothelial function was superior with pitavastatin compared to atorvastatin therapy. Pitavastatin could be a potentially better therapeutic choice for lipid-lowering and early alterations in endothelial function. Our study provides an important basis on which further trials involving larger numbers of patients may be studied prospectively.

Similar Articles

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

Author(s): Cholesterol Treatment Trialists’ (CTT) Collaboration, Baigent C, Blackwell L, Emberson J, Holland LE, et al.

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein

Author(s): Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, et al.

Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials

Author(s): Sattar N, Preiss D, Murray HM, Welsh P, Buckley BM, et al.

Effects of pitavastatin on adiponectin in patients with hyperlipidemia

Author(s): Inami N, Nomura S, Shouzu A, Omoto S, Kimura Y, et al.

Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice

Author(s): Ishihara Y, Ohmori K, Mizukawa M, Hasan AU, Noma T, et al.