Effectiveness of isoflurane in inducing delayed preconditioning against myocardial infarction in vivo

Author(s): Xia Z, Wang F, Luo T

Abstract

We read with great interest the article by Chiari et al.  1regarding a potential role of endothelial nitric oxide synthase in isoflurane-induced delayed preconditioning in rabbit myocardium. The authors are to be congratulated for performing an important study about the remote effects of isoflurane in attenuating myocardial infarct after acute coronary occlusion and reperfusion. In particular, they addressed the potential role of endothelial nitric oxide synthase and subsequently of nitric oxide in isoflurane-induced myocardial protection.

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