Laparoscopic ovarian drilling as first line treatment in infertile women with polycystic ovary syndrome

Author(s): Cleemann L, Lauszus FF, Trolle B


Laparoscopic ovarian drilling (LOD) is used as a first line of treatment, as a second line of treatment after patients have proved resistant to clomiphene or as a third line of treatment after failed ovulation induction with gonadotropins. We present the postoperative pregnancy rates of 57 women to evaluate a potential optimal time of LOD together with the other treatment regimens of infertile women with polycystic ovary syndrome (PCOS). Data on the preoperative and operative treatment, and background data were evaluated for their influence on pregnancy rates. The pregnancy rate was 61% among women with PCOS who had LOD. No difference was found in the clinical data between the women who became pregnant and those who did not. Likewise, no difference was found between the women who had pre- and/or postoperative medical ovulation treatment and those who had none. The median time to pregnancy after LOD was 135 days. LOD alone resolves infertility within 4-6 months in 50-60% of couples. A strategy with diagnostic laparoscopy and LOD as the first line of treatment of infertility in women with PCOS will shorten the time to pregnancy for many women, reduce the need for medical ovulation induction and enable diagnosis of those women with anatomic infertility, who can achieve pregnancy only by in vitro fertilization treatment.

Similar Articles

The application and development of ultrasonic scalpel

Author(s): Chen Y, Luo X, Shi W, Zhou Z

Surgical or medical treatment of polycystic ovary syndrome: a cost-benefit analysis

Author(s): Kovacs GT, Clarke S, Burger HG, Healy DL, Vollenhoven B

Electrocautery in polycystic ovary syndrome

Author(s): Tasaka K, Sakata M, Kurachi H, Komura H, Miyake A, et al.

Evaluation of adhesion formation after laparoscopic treatment of polycystic ovarian disease

Author(s): Gurgan T, Kisnisci H, Yarali H, Develioğlu O, Zeyneloğlu H, et al.

Treatment of anovulation due to polycystic ovarian syndrome by laparoscopic ovarian electrocautery

Author(s): Kovacs G, Buckler H, Bangah M, Outch K, Burger H, et al.

Periovarian adhesions following ovarian wedge resection or laparoscopic biopsy

Author(s): Portuondo JA, Melchor JC, Neyro JL, Alegre A

Adhesion formation after ovarian electrocauterization on patients with polycystic ovarian syndrome

Author(s): Dabirashrafi H, Mohamad K, Behjatnia Y, Moghadami-Tabrizi N