Author(s): Hsu HW, Butte NF, Wong WW, Moon JK, Ellis KJ, et al.
To investigate whether protein, carbohydrate, and fat metabolism was normalized in insulin-treated gestational diabetes mellitus (GDM), eight Hispanic women with GDM and eight healthy controls were studied at 32-36 wk of gestation and 6 wk postpartum. Net substrate utilization was measured using room respiration calorimetry. Exogenous substrate oxidation was determined by 13C recovered in breath CO2 from 13C-labeled leucine, glucose, and Hiolein. Women with GDM had higher 24-h oxygen consumption, carbon dioxide production, total energy expenditure, and basal metabolic rates than controls due to larger body mass. Adjusted for weight or fat-free mass, total energy expenditure, basal metabolic rate, and basal and 24-h whole body net protein, carbohydrate, and fat utilization did not differ between insulin-treated GDM subjects and controls in pregnancy or postpartum. Oxidation of [13C]leucine and [13C]glucose did not differ by group or pregnancy status. Recovery of exogenously administered [13C]Hiolein, a biosynthetic triglyceride, as breath 13CO2 was significantly lower in the GDM group antepartum and postpartum (P = 0.02), indicating lower oxidation of exogenous triglycerides in GDM.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/9227457
Author(s): Ghio A, Bertolotto A, Resi V, Volpe L, Di Cianni G
Author(s): Forsum E, Löf M
Author(s): Rebouche CJ
Author(s): Wutzke KD, Lorenz H
Author(s): Rinaldo P, Raymond K, al-Odaib A, Bennett MJ
Author(s): Talián GC, Komlósi K, Decsi T, Koletzko B, Melegh B
Author(s): Koumantakis E, Sifakis S, Koumantaki Y, Hassan E, Matalliotakis I, et al.
Author(s): Schoderbeck M, Auer B, Legenstein E, Genger H, Sevelda P, et al.
Author(s): Pappa KI, Anagnou NP, Salamalekis E, Bikouvarakis S, Maropoulos G, et al.
Author(s): Evangeliou A, Gourgiotis D, Karagianni C, Markouri M, Anogianaki N, et al.
Author(s): Schulpis KH, Papakonstantinou ED, Vlachos GD, Vlachos DG, Antsaklis A, et al.
Author(s): Guerci B, Benichou M, Floriot M, Bohme P, Fougnot S, et al.
Author(s): Lagerstedt SA, Hinrichs DR, Batt SM, Magera MJ, Rinaldo P, et al.
Author(s): Soltész G, Melegh B, Sándor A
Author(s): Eng J
Author(s): Winter SC, Linn LS, Helton E
Author(s): Rebouche CJ, Engel AG
Author(s): Pedersen SB, Kristensen K, Hermann PA, Katzenellenbogen JA, Richelsen B
Author(s): Gil-Sánchez A, Koletzko B, Larqué E
Author(s): Herrera E, Amusquivar E, López-Soldado I, Ortega H
Author(s): Herrera E
Author(s): Gin H, Vambergue A, Vasseur C, Rigalleau V, Dufour P, et al.
Author(s): Poorabbas A, Fallah F, Bagdadchi J, Mahdavi R, Aliasgarzadeh A, et al.
Author(s): Sánchez-Vera I, Bonet B, Viana M, Quintanar A, Martín MD, et al.
Author(s): Ortega-Senovilla H, Alvino G, Taricco E, Cetin I, Herrera E
Author(s): Ringseis R, Keller J, Eder K
Author(s): Grube M, Meyer Zu Schwabedissen H, Draber K, Präger D, Möritz KU, et al.
Author(s): Oey NA, den Boer ME, Ruiter JP, Wanders RJ, Duran M, et al.
Author(s): Oey NA, den Boer ME, Wijburg FA, Vekemans M, Augé J, et al.