Author(s): Takeuchi S, Futamura N, Takubo S, Noda N, Minoura H, et al.
Objective: To evaluate the endocrinologic profile and reproductive outcome after laparoscopic drilling using a harmonic scalpel for polycystic ovarian syndrome (PCOS) in clomiphene-resistant infertile women.
Study design: We performed a prospective, randomized study of 34 infertile women with PCOS. Group A (17 women) underwent laparoscopic ovarian drilling using a harmonic scalpel laser. Group B (control group, 17 women) underwent laparoscopic ovarian drilling using a neodymium-yttrium-aluminum-garnet laser. Change in the hormonal profile after surgery, ovulation rate and pregnancy rate were compared between groups A and B.
Results: LH and testosterone serum levels and the LH-FSH ratio showed a statistically significant reduction after surgery, and the spontaneous ovulation rate was 94% in both groups. The cumulative pregnancy rates within two years of follow-up were 77% in group A and 60% in group B.
Conclusion: Laparoscopic ovarian drilling using a harmonic scalpel is an effective treatment for PCOS in clomiphene-resistant, anovulatory women: it results in ovulation and conception without major complications.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/12418063
Author(s): Van der Veen F, Bayrama N, Van Welya M, Bossuytb P
Author(s): Felemban A, Tan SL, Tulandi T
Author(s): Setji TL, Brown AJ
Author(s): Cleemann L, Lauszus FF, Trolle B
Author(s): Jansen FW, Trimbos-Kemper T, Trimbos JB
Author(s): Chen Y, Luo X, Shi W, Zhou Z
Author(s): Kandil M, Selim M
Author(s): Api M, Görgen H, Cetin A
Author(s): Kovacs GT, Clarke S, Burger HG, Healy DL, Vollenhoven B
Author(s): Kucuk M, Kilic-Okman T
Author(s): Daniell JF, Miller W
Author(s): Utsunomiya T, Sumioki H, Taniguchi I
Author(s): Abdel Gadir A, Mowafi RS, Alnaser HM, Alrashid AH, Alonezi OM, et al.
Author(s): Tasaka K, Sakata M, Kurachi H, Komura H, Miyake A, et al.
Author(s): Gurgan T, Kisnisci H, Yarali H, Develioğlu O, Zeyneloğlu H, et al.
Author(s): Kovacs G, Buckler H, Bangah M, Outch K, Burger H, et al.
Author(s): Ostrzenski A
Author(s): Armar NA, Lachelin G
Author(s): Gjonnaess H
Author(s): Portuondo JA, Melchor JC, Neyro JL, Alegre A
Author(s): Keckstein J
Author(s): Naether OG, Baukloh V, Fischer R, Kowalczyk T
Author(s): Gurgan T, Urman B, Aksu T, Yarali H, Develioglu O, et al.
Author(s): Naether OG, Fischer R
Author(s): Dabirashrafi H, Mohamad K, Behjatnia Y, Moghadami-Tabrizi N
