Author(s): Sahraian MA, Khorramnia S, Ebrahim MM, Moinfar Z, Lotfi J, et al.
Background:Iran was formerly considered to be located in a low prevalence zone for multiple sclerosis (MS). During the last decade the number of patients has increased. This study was conducted to estimate the prevalence of MS in the capital city of the country.
Methods:We re-evaluated the files of all patients who had registered at the Iranian Multiple Sclerosis Society during a 10-year period.
Results:8,146 patients (72.3% female, 27.7% male) with a female-to-male ratio of 2.60 had registered. Mean age of disease onset was 27.24 (SD: 8.32). A relapsing-remitting pattern was recognized in 84.9% of the patients. The number of new registrations tripled from 2002 to 2008 and the female-to-male ratio increased from 2 to 3.12. The prevalence of MS in Tehran is estimated to be at least 51.9 per 100,000. Visual impairment was the main presenting symptom.
Conclusions:It seems that the prevalence of MS has increased to a medium-to-high risk level in Iran. The mean age of onset was similar to other studies but the calculated prevalence of early onset MS was increased. The cumulative data indicates that the female-to-male ratio is increasing annually.
Referred From: https://pubmed.ncbi.nlm.nih.gov/21071949/
Author(s): Sundström P, Nyström M, Ruuth K, Lundgren E
Author(s): Hedström AK, Bäärnhielm M, Olsson T, Alfredsson L
Author(s): Alotaibi S, Kennedy J, Tellier R, Stephens D, Banwell B
Author(s): Langer-Gould A, Albers KB, Van Den Eeden SK, Nelson LM
Author(s): Muthian G, Raikwar HP, Rajasingh J, Bright JJ
Author(s): Niino M, Miyazaki Y, Fukazawa T, Kikuchi S
Author(s): Ascherio A, Munger K
Author(s): Islam T, Gauderman WJ, Cozen W, Hamilton AS, Burnett ME, et al.
Author(s): Gourraud PA, Harbo HF, Hauser SL, Baranzini SE
Author(s): Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A
Author(s): Dwyer T, van der Mei I, Ponsonby AL, Taylor BV, Stankovich J, et al.
Author(s): Hayes CE
Author(s): Etemadifar M, Janghorbani M, Shaygannejad V, Ashtari F
Author(s): Moghtaderi A, Rakhshanizadeh F, Shahraki-Ibrahimi S
Author(s): Kazemi A, Sharifi F, Jafari N, Mousavinasab N
Author(s): Etemadifar M, Janghorbani M, Shaygannejad V, Ashtari F
Author(s): Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, et al.
Author(s): Paty DW, Oger JJ, Kastrukoff LF, Hashimoto SA, Hooge JP, et al.
Author(s): Cashman KD, Hill TR, Lucey AJ, Taylor N, Seamans KM, et al.
Author(s): Saka M, Saka M, Koseler E, Metin S, Bilen S, et al.
Author(s): Smolders J, Menheere P, Kessels A, Damoiseaux J, Hupperts R
Author(s): Orton SM, Morris AP, Herrera BM, Ramagopalan SV, Lincoln MR, et al.
Author(s): Smolders J, Menheere P, Kessels A, Damoiseaux J, Hupperts R
Author(s): van der Mei IA, Ponsonby AL, Dwyer T, Blizzard L, Taylor BV, et al.
Author(s): Munger KL, Chitnis T, Frazier AL, Giovannucci E, Spiegelman D, et al.
Author(s): Kampman MT, Wilsgaard T, Mellgren SI
Author(s): van der Mei IA, Ponsonby AL, Dwyer T, Blizzard L, Simmons R, et al.
Author(s): Hayes CE, Donald Acheson E
