Author(s): Krupp LB, Serafin DJ, Christodoulou C
Fatigue is an extremely prevalent issue for multiple sclerosis (MS) patients. Fatigue can affect quality of life, depression, anxiety, motor function and sleep patterns. There are a number of available rating scales designed to detect and assess fatigue. However, the pathophysiology of fatigue is still not completely understood and the treatment of this symptom remains difficult. A number of clinical trials for fatigue in MS have shown some benefit with different interventions, including medication, physical activity and cognitive-behavioral therapy. Nonetheless, further research and the development of more targeted therapies are needed to improve the management of fatigue.
Referred From: https://pubmed.ncbi.nlm.nih.gov/20819014/
Author(s): Kos D, Kerckhofs E, Nagels G, D'hooghe MB, Ilsbroukx S
Author(s): Merkelbach S, Haensch CA, Hemmer B, Koehler J, König NH, et al.
Author(s): Veauthier C, Radbruch H, Gaede G, Pfueller CF, Dörr J, et al.
Author(s): Dallmeijer AJ, Dekker J, Roorda LD, Knol DL, van Baalen B, et al.
Author(s): Brown RF, Valpiani EM, Tennant CC, Dunn SM, Sharrock M, et al.
Author(s): Flachenecker P, Wolf A, Krauser M, Hartung HP, Reiners K
Author(s): Kale N, Magana S, Agaoglu J, Tanik O
Author(s): Kluger BM, Krupp LB, Enoka RM
Author(s): Guthrie TC, Nelson DA
Author(s): Marino FE
Author(s): Davis SL, Wilson TE, White AT, Frohman EM
Author(s): Flensner G, Ek AC, Söderhamn O, Landtblom AM
Author(s): Schwid SR, Petrie MD, Murray R, Leitch J, Bowen J, et al.
Author(s): White AT, Wilson TE, Davis SL, Petajan JH
Author(s): Chua EC, Tan WQ, Yeo SC, Lau P, Lee I, et al.
Author(s): Calabrese M, Rinaldi F, Grossi P, Mattisi I, Bernardi V, et al.
Author(s): McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, et al.
Author(s): Kurtzke JF
Author(s): Penner IK, Raselli C, Stöcklin M, Opwis K, Kappos L, et al.
Author(s): Monge-Argilés JA, Palacios-Ortega F, Vila-Sobrino JA, Matias-Guiu J
Author(s): Capello E, Gardella M, Leandri M, Abbruzzese G, Minatel C, et al.
Author(s): Flensner G, Lindencrona C
Author(s): Grahn DA, Murray JV, Heller HC
Author(s): Schwid SR, Petrie MD, Murray R, Leitch J, Bowen J, et al.
Author(s): Reynolds LF, Short CA, Westwood DA, Cheung SS
Author(s): Nilsagård Y, Denison E, Gunnarsson LG
Author(s): Sumowski JF, Leavitt VM2
Author(s): Beenakker EA, Oparina TI, Hartgring A, Teelken A, Arutjunyan AV, et al.
