Thermal analgesic effects from weak, complex magnetic fields and pharmacological interactions

Author(s): Martin LJ, Koren SA, Persinger MA


In several experiments, robust analgesia (equivalent to about 4 mg/kg of morphine) in male rats to thermal stimuli following exposures to weak (1 microT) complex magnetic fields was explored. The analgesia occurred when patterns of magnetic fields with burst-firing-like configurations were presented for 30 min once every approximately 4 s. The analgesic effects were intensity dependent. A different frequency-modulated pattern produced analgesia more quickly. The analgesic effects following exposure to the burst-firing magnetic fields were augmented conspicuously by preinjections of morphine (4 mg/kg) or agmatine (10 mg/kg), but blocked by naloxone (1 mg/kg). The results of these experiments suggest that rational design of the temporal structure of weak magnetic fields may be a novel, inexpensive, and reliable technique for elevating thresholds to some classes of painful stimuli.

Similar Articles

[Structure of the glial cells in the nervous system of parasitic and free-living flatworms]

Author(s): Biserova NM, Gordeev II, KornevaZhV, Sal'nikova MM

Neuropharmacology and behavior in planarians: translations to mammals

Author(s): Buttarelli FR, Pellicano C, Pontieri FE

Cocaine withdrawal in Planaria

Author(s): Raffa RB, Valdez JM

Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin

Author(s): AdamoAM,Paez PM, Escobar Cabrera OE, Wolfson M, Franco PG, et al.

Learning induces long-term potentiation in the hippocampus

Author(s): Whitlock JR, Heynen AJ, Shuler MG, Bear MF