Author(s): Nie K, Zhang Y, Wang L, Zhao J, Huang Z, et al.
Cognitive dysfunction is one of the most critical clinical manifestations of Parkinson's disease (PD), and its accurate and efficient diagnosis is crucial for treatment. We evaluated the psychometric properties of the Beijing version of the Montreal Cognitive Assessment (BJ-MoCA) in 123 Chinese patients with idiopathic PD. The internal consistency and convergent validity of the BJ-MoCA were examined and psychometric characteristics of BJ-MoCA scores were analyzed in PD patients with ''normal'' Mini-Mental State Examination (MMSE) scores. More than half (56.9%) of the patients with normal MMSE scores showed cognitive impairment in multiple cognitive domains, including visuospatial and executive functions, naming, attention, language, delayed recall, and orientation. The impaired delayed recall was less likely to occur in newly diagnosed patients, and the orientation ability in patients with early onset was rarely affected. The multivariate regression analysis revealed that the age of symptom onset and disease severity were independent predictors of cognitive impairment. Thus, the current findings demonstrate that the BJ-MoCA is a reliable tool for screening cognitive dysfunction in Chinese patients with idiopathic PD. It is more sensitive than the MMSE for screening early cognitive decline in non-memory dysfunction.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/22959678
Author(s): Lee MA, Walker RW, Hildreth TJ, Prentice WM
Author(s): Bair MJ, Robinson RL, Katon W, Kroenke K
Author(s): McWilliams LA, Cox BJ, Enns MW
Author(s): Hanagasi HA, Akat S, Gurvit H, Yazici J, Emre M
Author(s): Nieoullon A
Author(s): Schneier FR, Liebowitz MR, Abi-Dargham A, Zea-Ponce Y, Lin SH, et al.
Author(s): Roh JH, Kim BJ, Jang JH, Seo WK, Lee SH, et al.
Author(s): Hara T, Hirayama M, Mizutani Y, Hama T, Hori N, et al.
Author(s): Erro R, Santangelo G, Picillo M, Vitale C, Amboni M, et al.
Author(s): Hughes AJ, Daniel SE, Kilford L, Lees AJ
Author(s): Fahn S; Parkinson Study Group
Author(s): Chaudhuri KR, Martinez-Martin P, Schapira AH, Stocchi F, Sethi K, et al.
Author(s): Melzack R
Author(s): Cleeland CS, Ryan KM
Author(s): Smeding HM, Esselink RA, Schmand B, Koning-Haanstra M, Nijhuis I, et al.
Author(s): Ford B
Author(s): Airavaara M, Harvey BK, Voutilainen MH, Shen H, Chou J, et al.
Author(s): Ha AD, Jankovic J
Author(s): Santos-García D, Abella-Corral J, Aneiros-Díaz Á, Santos-Canelles H, Llaneza-González MA, et al.
Author(s): Yong MH, Allen JC Jr, Prakash KM, Tan EK
Author(s): Jarcho JM, Mayer EA, Jiang ZK, Feier NA, London ED
Author(s): Mylius V, Brebbermann J, Dohmann H, Engau I, Oertel WH, et al.
Author(s): Nutt JG
Author(s): Lim SY, Farrell MJ, Gibson SJ, Helme RD, Lang AE, et al.
Author(s): Romenets SR, Wolfson C, Galatas C, Pelletier A, Altman R, et al.
Author(s): Raudino F