Author(s): Mazzanti B, Aldinucci A, Biagioli T, Barilaro A, Urbani S, et al.
MSCs have been proposed as possible treatment in MS: In this study MSCs obtained from 10 MS patients and 6 healthy donors (HD) were compared in terms of phenotypical and functional characteristics. We show that MSCs isolated from MS and HD differ significantly for IP10 production. Therefore, although MSCs isolated from MS patients exhibit the same properties of HD MSCs in terms of proliferation, phenotype, in vitro differentiation, TLR expression, immunosuppressive ability, inhibition of DC differentiation and activation, the use of autologous MSCs in cell therapy of autoimmune diseases should be submitted to attentive evaluation and treatment.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/18562015
Author(s): Rice CM, Mallam EA, Whone AL, Walsh P, Brooks DJ, et al.
Author(s): Martino G, Franklin RJ, Baron Van Evercooren A, Kerr DA; Stem Cells in Multiple Sclerosis (STEMS) Consensus Group
Author(s): Karussis D, Petrou P, Kassis I
Author(s): Laroni A, Novi G, Kerlero de Rosbo N, Uccelli A
Author(s): Gögel S, Gubernator M, Minger SL
Author(s): Keirstead HS, Nistor G, Bernal G, Totoiu M, Cloutier F, et al.
Author(s): De Coppi P1, Bartsch G Jr, Siddiqui MM, Xu T, Santos CC, et al.
Author(s): Takahashi K, Yamanaka S
Author(s): Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, et al.
Author(s): Devine SM, Cobbs C, Jennings M, Bartholomew A, Hoffman R
Author(s): Koç ON, Day J, Nieder M, Gerson SL, Lazarus HM, et al.
Author(s): Auletta JJ, Bartholomew AM, Maziarz RT, Deans RJ, Miller RH, et al.
Author(s): Mallam E, Kemp K, Wilkins A, Rice C, Scolding N
Author(s): Carrai V, Donnini I, Mazzanti B, Alterini R, Amato M P, et al.
Author(s): Rice CM, Scolding NJ
Author(s): Djouad F, Plence P, Bony C, Tropel P, Apparailly F, et al.
Author(s): Hare J M, Traverse J H, Henry T D, Dib N, Strumpf R K, et al.
Author(s): Carrion FA, Figueroa FE
Author(s): Liang J, Zhang H, Hua B, Wang H, Wang J, et al.
Author(s): Riordan NH, Ichim TE, Min WP, Wang H, Solano F, et al.
Author(s): Kim Y, Kim H, Cho H, Bae Y, Suh K, et al.
Author(s): Keyser KA, Beagles KE, Kiem HP
Author(s): Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, et al.
Author(s): Zhang J, Li Y, Lu M, Cui Y, Chen J, et al.
Author(s): Rafei M, Campeau P M, Aguilar-Mahecha A, Buchanan M, Williams P, et al.
Author(s): Darlington PJ, Boivin MN, Renoux C, François M, Galipeau J, et al.