Author(s): Neu I, Mallinger J, Wildfeuer A, Mehlber L
The concentration of the leukotrienes B4 (LTB4) and C4 (LTC4) was measured in the cerebrospinal fluid (CSF) of 38 multiple sclerosis (MS) patients and 51 with other neurological diseases. The LTB4 and LTC4 levels were significantly elevated in MS compared with the controls. The findings suggest that lipoxygenase products might play a pathogenetic role in the early, encephalitogenic phase of MS. The administration of lipoxygenase inhibitors or leukotriene antagonists might well open new perspectives for the treatment of MS.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/1336293
Author(s): Hassan-Smith G, Douglas MR
Author(s): Río J, Comabella M, Montalban X
Author(s): Yadav V, Shinto L, Bourdette D
Author(s): Leong EM, Semple SJ, Angley M, Siebert W, Petkov J, et al.
Author(s): Marrie RA, Hadjimichael O, Vollmer T
Author(s): Schwarz S, Knorr C, Geiger H, Flachenecker P
Author(s): Shinto L, Calabrese C, Morris C, Yadav V, Griffith D, et al.
Author(s): Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, Mehrangiz EM, Baradaran B, et al.
Author(s): vonGeldern G, Mowry EM
Author(s): Fetterman JW Jr, Zdanowicz MM
Author(s): Lands WE
Author(s): Calder PC
Author(s): Burdge GC, Calder PC
Author(s): Calder PC
Author(s): Yates CM, Calder PC, Ed Rainger G
Author(s): Gorjão R, Azevedo-Martins AK, Rodrigues HG, Abdulkader F, Arcisio-Miranda M, et al.
Author(s): Iwami D, Nonomura K, Shirasugi N, Niimi M
Author(s): Bates D, Cartlidge NE, French JM, Jackson MJ, Nightingale S, et al.
Author(s): Gallai V, Sarchielli P, Trequattrini A, Franceschini M, Floridi A, et al.
Author(s): Weinstock-Guttman B, Baier M, Park Y, Feichter J, Lee-Kwen P, et al.
Author(s): Sierra S, Lara-Villoslada F, Comalada M, Olivares M, Xaus J
Author(s): Verlengia R, Gorjão R, Kanunfre CC, Bordin S, Martins De Lima T, et al.
