Author(s): Godoy DA, Pinero G, Di Napoli M
Background and purpose:A clinical grading scale for intracerebral hemorrhage (ICH), formally ICH score, was recently developed showing to predict 30-day mortality in a simple and reliable manner. The aim of the present study was to validate the original ICH (oICH) score in an independent cohort of patients from a developing country assessing 30-day mortality and 6-month functional outcome and whether its modifications can improve prediction.
Methods:Consecutive patients admitted with acute ICH between January 1, 2003, and July 31, 2004, were prospectively included. oICH score was applied and 2 modified ICH (mICH) scores were created with the same variables, except localization, of the oICH score but with different cutoff values. Outcome was assessed as 30-day mortality and 6-month good outcome (Glasgow Outcome Scale [GOS] 4 to 5).
Results:A total of 153 patients were included during study period. Thirty-day mortality rate was 34.6% (n=53), and 59 patients (38.6%) had good functional outcome (GOS 4 to 5) at 6 months. The oICH and mICH scores predicted mortality equally well. According to Youden's index (J), the oICH score was a reliable predictor for mortality (J=0.59) but less reliable for predicting good outcome (J=0.54). The mICH scores were equal in predicting mortality but better for predicting good outcome than the oICH score (J=0.60).
Conclusions:oICH score also confirms its validity in a socially and culturally different population. Modifications of oICH do not improve its 30-day mortality prediction but improve its ability to predict good functional outcome at 6 months.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/16514104
Author(s): Dennis MS
Author(s): Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, et al.
Author(s): Mayer SA
Author(s): Aronowski J, Hall CE
Author(s): Wang J, Dore S
Author(s): Gong C, Hoff JT, Keep RF
Author(s): Keep RF, Xi G, Hua Y, Hoff JT
Author(s): Castillo J, Davalos A, Alvarez-Sabin J, Pumar JM, Leira R, et al.
Author(s): Silva Y, Leira R, Tejada J, Lainez JM, Castillo J, et al.
Author(s): Leira R, Davalos A, Silva Y, Gil-Peralta A, Tejada J
Author(s): Leira R, Castellanos M, Alvarez-Sabin J, Diez-Tejedor E, Davalos A, et al.
Author(s): Castellanos M, Leira R, Tejada J, Gil-Peralta A, Davalos A, et al.
Author(s): Di Napoli M, Schwaninger M, Cappelli R, Ceccarelli E, Di Gianfilippo G, et al.
Author(s): Canova CR, Courtin C, Reinhart WH
Author(s): Steiner T, Kaste M, Forsting M, Mendelow D, Kwiecinski H, et al.
Author(s): Knaus WA, Draper EA, Wagner DP, Zimmerman JE
Author(s): Hemphill JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC
Author(s): Di Napoli M, Papa F, Bocola V
Author(s): Di Napoli M, Papa F, Bocola V
Author(s): Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, et al.
Author(s): Cheung RT, Zou LY
Author(s): Graeb DA, Robertson WD, Lapointe JS, Nugent RA, Harrison PB
Author(s): Diringer MN, Edwards DF, Zazulia AR
Author(s): Godoy DA, Pinero GR, Svampa S, Papa F, Di Napoli M
Author(s): Maiuri F, Corriero G, Passarelli F, Cirillo S, Astarita G
Author(s): Bestue-Cardiel M, Martin-Martinez J, Iturriaga-Heras C, Ara-Callizo JR, Oliveros-Juste A
Author(s): Suzuki S, Kelley RE, Dandapani BK, Reyes-Iglesias Y, Dietrich WD, et al.
Author(s): Power C, Henry S, Del Bigio MR, Larsen PH, Corbett D, et al.
Author(s): Wasserman JK, Zhu X, Schlichter LC
Author(s): Mackenzie JM, Clayton JA
Author(s): Sinn DI, Lee ST, Chu K, Jung KH, Kim EH, et al.
Author(s): Abilleira S, Montaner J, Molina CA, Monasterio J, Castillo J, et al.
Author(s): Qureshi AI, Suri MF, Ling GS, Khan J, Guterman LR, et al.