TM4 microarray software suite

Author(s): Saeed AI, Bhagabati NK, Braisted JC, Liang W, Sharov V, et al.

Abstract

Powerful specialized software is essential for managing, quantifying, and ultimately deriving scientific insight from results of a microarray experiment. We have developed a suite of software applications, known as TM4, to support such gene expression studies. The suite consists of open-source tools for data management and reporting, image analysis, normalization and pipeline control, and data mining and visualization. An integrated MIAME-compliant MySQL database is included. This chapter describes each component of the suite and includes a sample analysis walk-through.

Similar Articles

Cerebral vasospasm following aneurysmal subarachnoid hemorrhage

Author(s): Kassell NF, Sasaki T, Colohan AR, Nazar G

Altered patterns of gene expression in response to myocardial infarction

Author(s): Stanton LW, Garrard LJ, Damm D, Garrick BL, Lam A, et al.

Genomics of human intracranial aneurysm wall

Author(s): Shi C, Awad IA, Jafari N, Lin S, Du P, et al.

Bioconductor: open software development for computational biology and bioinformatics

Author(s): Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al.

Heme oxygenase-1 gene induction as an intrinsic regulation against delayed cerebral vasospasm in rats

Author(s): Suzuki H, Kanamaru K, Tsunoda H, Inada H, Kuroki M, et al.

Gene expression and molecular changes in cerebral arteries following subarachnoid hemorrhage in the rat

Author(s): Vikman P, Beg S, Khurana TS, Hansen-Schwartz J, Edvinsson L

Gene expression in a canine basilar artery vasospasm model: a genome-wide network-based analysis

Author(s): Sasahara A, Kasuya H, Krischek B, Tajima A, Onda H, et al.

Global quantification of mammalian gene expression control

Author(s): Schwanhausser B, Busse D, Li N, Dittmar G, Schuchhardt J, et al.

Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage

Author(s): Borel CO, McKee A, Parra A, Haglund MM, Solan A, et al.

Oxidative stress activates STAT1 in basilar arteries after subarachnoid hemorrhage

Author(s): Osuka K, Watanabe Y, Usuda N, Atsuzawa K, Wakabayashi T, et al.

Cerebral artery spasm

Author(s): Hughes JT, Schianchi PM

Stroke: anatomy of a catastrophic event

Author(s): Zhang J, Lewis A, Bernanke D, Zubkov A, Clower B

Neuroprotection by osteopontin in stroke

Author(s): Meller R, Stevens SL, Minami M, Cameron JA, King S, et al.

Expression, roles, receptors, and regulation of osteopontin in the kidney

Author(s): Xie Y, Sakatsume M, Nishi S, Narita I, Arakawa M, et al.

Apoptosis of endothelial cells in vessels affected by cerebral vasospasm

Author(s): Zubkov AY, Ogihara K, Bernanke DH, Parent AD, Zhang J

Morphological changes of cerebral arteries in a canine double hemorrhage model

Author(s): Zubkov AY, Tibbs RE, Clower B, Ogihara K, Aoki K, et al.

Barrier disruption in the major cerebral arteries following experimental subarachnoid hemorrhage

Author(s): Sasaki T, Kassell NF, Yamashita M, Fujiwara S, Zuccarello M

Barrier disruption in the major cerebral arteries during the acute stage after experimental subarachnoid hemorrhage

Author(s): Sasaki T, Kassell NF, Zuccarello M, Nakagomi T, Fijiwara S, et al.

Immune complexes and complement activation following rupture of intracranial saccular aneurysms

Author(s): Ostergaard JR, Kristensen BO, Svehag SE, Teisner B, Miletic T