Related Subjects
 

Trace metal bioaccumulation: models, metabolic availability and toxicity

Author(s): Rainbow PS

Abstract

Aquatic invertebrates take up and accumulate trace metals whether essential or non-essential, all of which have the potential to cause toxic effects. Subsequent tissue and body concentrations of accumulated trace metals show enormous variability across metals and invertebrate taxa. Accumulated metal concentrations are interpreted in terms of different trace metal accumulation patterns, dividing accumulated metals into two components — metabolically available metal and stored detoxified metal. Examples of different accumulation patterns are described from crustaceans but have a general applicability to all aquatic invertebrates. Toxicity does not depend on total accumulated metal concentration but is related to a threshold concentration of internal metabolically available metal. Toxicity ensues when the rate of metal uptake from all sources exceeds the combined rates of detoxification and excretion (if present) of the metal concerned. The biodynamic model of trace metal bioaccumulation allows the prediction and explanation of widely differing accumulated trace metal concentrations in organisms, combining geochemical analyses of environmental metal concentrations with the measurement of key physiological parameters for a species from the site under consideration. The combination of the biodynamic model as a unified explanation of metal bioaccumulation with an understanding of the relationship between accumulation and toxicity sets the stage for a realistic understanding of the significance of trace metal concentrations in aquatic invertebrates.

Similar Articles

Molluscs in biological monitoring of water quality

Author(s): Salánki J, Farkas A, Kamardina T, Rózsa KS

Metal Contamination in Aquatic Environments

Author(s): Luoma SN, Rainbow PS

Molluscs as multidisciplinary models in environmental toxicology

Author(s): Rittschof D, McClellan-Green P

Response of Mytilus galloprovincialis (L

Author(s): Anestis A, Pörtner HO, Karagiannis D, Angelidis P, Staikou A, et al.

Integrated use of biomarkers (superoxide dismutase, catalase and lipid peroxidation)

Author(s): Vlahogianni TM, Dassenakis M, Scoullos J, Valavanidis A

Monitoring the biochemical and cellular responses of marine bivalves during thermal stress by using biomarkers

Author(s): Dimitriadis VK, Gougoula C, Anestis A, Pörtner HO, Michaelidis B

Biomarker responses of mussels exposed to earthquake disturbances

Author(s): Chandurvelan R, Marsden ID, Glover CN, Gaw S

Aquat Toxicol 142-143: 283-293

Author(s): Chandurvelan R, Marsden ID, Gaw S, Glover CN (2013 b) Waterborne cadmium impacts immunocytotoxic and cytogenotoxic endpoints in green-lipped mussel, Perna canaliculus

Metals, toxicity and oxidative stress

Author(s): Valko M, Morris H, Cronin MTD

Spatial and temporary trends on contaminants in mussel sampled around the Icelandic coastline

Author(s): Sturludottir E, Gunnlaugsdottir H, Jorundsdottir HO, Magnusdottir EV, Olafsdottir K, et al.

Glutathione peroxidase and catalase modulate the genotoxicity of arsenic

Author(s): Wang TS, Shu YF, Liu YC, Jan KY, Huang H

Heavy metals and glutathione metabolism in mussel tissues

Author(s): Canesi L, Viarengo A, Leonzio C, Filippelli M, Gallo G