Recommended Conferences

Neuroscience Psychiatry

Dubai, UAE

2nd International Conference on Clinical Psychiatry

Miami, USA

Psychology and Mental Health

Chicago, USA
Related Subjects
 

Early onset cannabis use and progression to other drug use in a sample of Dutch twins

Author(s): Lynskey MT, Vink JM, Boomsma DI

Abstract

One possible explanation of the commonly reported associations between early onset cannabis use and elevated risks of other illicit drug use is that early onset cannabis use increases access and availability to other drugs. It was this argument that in part motivated policy changes in the Netherlands that led to the de facto legalization of cannabis there. This study examines, using a co-twin control design, whether previously observed associations between early onset cannabis use and elevated lifetime rates of other illicit drug use would also be observed in a sample of 219 same sex Dutch twin pairs discordant for cannabis use before age 18. After adjustment for covariates, rates of lifetime party drug use (OR=7.4, 95% CI=2.3–23.4), hard drug use (OR=16.5, 95% CI=2.4–111.3), but not regular cannabis use (OR=1.3, 95% CI=0.3–5.1) were significantly elevated in individuals who reported early onset cannabis use, relative to their co-twin who had not used cannabis by age 18. The elevated odds of subsequent illicit drug use in early cannabis users relative to their non early using co-twins suggests that this association could not be explained by common familial risk factors, either genetic or environmental, for which our co-twin methodology provided rigorous control.

Similar Articles

A role for cannabinoid CB1 receptors in mood and anxiety disorders

Author(s): Witkin JM, Tzavara ET, Nomikos GG

Adverse health effects of non-medical cannabis use

Author(s): Hall W, Degenhardt L

Parietal lobe volume deficits in adolescents with schizophrenia and adolescents with cannabis use disorders

Author(s): Kumra S, Robinson P, Tambyraja R, Jensen D, Schimunek C, et al.

Daily use, especially of high-potency cannabis, drives the earlier onset of psychosis in cannabis users

Author(s): Di Forti M, Sallis H, Allegri F, Trotta A, Ferraro L, et al.

Prevalence and intensity of basic symptoms among cannabis users: An observational study

Author(s): Martinotti G, Di Iorio G, Tedeschi D, De Berardis D, Niolu C, et al.

Rates of psychiatric comorbidity among U

Author(s): Agosti V, Nunes E, Levin F

Cannabis use and depression: a longitudinal study of a national cohort of Swedish conscripts

Author(s): Manrique-Garcia E, Zammit S, Dalman C, Hemmingsson T, Allebeck P

Escalation of drug use in early-onset cannabis users vs

Author(s): Lynskey MT, Heath AC, Bucholz KK, Slutske WS, Madden PA, et al.

A co twin-control analysis of drug use and abuse/dependence risk associated with early-onset cannabis use

Author(s): Grant JD, Lynskey MT, Scherrer JF, Agrawal A, Heath AC, et al.

Cannabis use and risk of psychotic or affective mental health outcomes: A systematic review

Author(s): Moore THN, Zammit S, Lingford-Hughes A, Barnes TRE, Jones PB

Genetic predisposition to schizophrenia associated with increased use of cannabis

Author(s): Power RA, Verweij KJH, Zuhair M, Montgomery GW, Henders AK, et al.

The association between cannabis use and depression: A systematic review and meta-analysis of longitudinal studies

Author(s): Lev-Ran S, Roerecke M, Le Foll B, George TP, McKenzie K, et al.

Major depression: The relative contribution of gender, MDMA and cannabis use

Author(s): Durdle H, Lundahl LH, Johanson CE, Tancer M

Relief-oriented use of marijuana by teens

Author(s): Bottorff JL1, Johnson JL, Moffat BM, Mulvogue T

Motives for drug use among light and heavy users

Author(s): Nail RL, Gunderson EK, Kolb D

Risk factors predicting changes in marijuana involvement in teenagers

Author(s): Van den Bree, Marianne BM, Wallace BP

Affect dysregulation in cannabis abusers: A study in adolescents and young adults

Author(s): Dorard G, Berthoz S, Phan O, Corcos M, Bungener C

Adolescent depression and risk factors

Author(s): Field T, Diego M, Sanders C

Cannabis, motivation and life satisfaction in an internet sample

Author(s): Barnwell SS, Earleywine M, Wilcox R

Sequencing of substance use and affective morbidity in 166 first episode bipolar I disorder patients

Author(s): Baethge C, Hennen J, Khalsa HM, Salvatore P, Tohen M, et al.

Adverse health effects of marijuana use

Author(s): Volkow ND, Baler RD, Compton WM, Weiss SR