Author(s): Rouhl RP, van Oostenbrugge RJ, Damoiseaux J, Tervaert JW, Lodder J
Background and purpose: Stroke is the leading cause of disability in the Western world; however, few therapies are at hand to decrease this burden.
Summary of review: Endothelial progenitor cells (EPCs) have been introduced in cardiovascular medicine as factotums. EPCs can repair damaged endothelium and attenuate the development and progression of atherosclerosis. Also, EPCs can form new vessels in ischemic areas and thus promote recovery after ischemic events. In stroke, however, EPC research is limited. In our overview, we provide background information on EPC use as a risk marker and as a potential therapeutic agent.
Conclusions: In our opinion, the lack of EPC studies in stroke should instigate vascular neurologists to participate in EPC research, as EPCs could also change pathophysiological concepts and improve clinical treatments in vascular neurology.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/18451350
Author(s): Davenport R, Dennis M
Author(s): Sudlow CL, Warlow CP
Author(s): Fagan SC, Morgenstern LB, Petitta A, Ward RE, Tilley BC, et al.
Author(s): Hess DC, Wang S, Hamilton W, Lee S, Pardue C, et al.
Author(s): Wang S, Gross H, Lee SB, Pardue C, Waller J, et al.
Author(s): Borlongan CV, Fournier C, Stahl CE, Yu G, Xu L, et al.
Author(s): Wang X, Rosell A, Lo EH
Author(s): Switzer JA, Hall C, Gross H, Waller J, Nichols FT, et al.
Author(s): Leira EC, Hess DC, Torner JC, Adams HP Jr
Author(s): Henninger N, Chowdhury N, Fisher M, Moonis M
Author(s): Wu O, Langhorne P
Author(s): Matsukawa N, Yasuhara T, Hara K, Xu L, Maki M, et al.
Author(s): Hill MD, Moy CS, Palesch YY, Martin R, Dillon CR, et al.
Author(s): Toda H, Takahashi J, Iwakami N, Kimura T, Hoki S, et al.
Author(s): Ferrari A, Ehler E, Nitsch RM, Götz J
Author(s): Borlongan CV, Tajima Y, Trojanowski JQ, Lee VMY, Sanberg PR
Author(s): Veizovic T, Beech JS, Stroemer RP, Watson WP, Hodges H
Author(s): Modo M, Stroemer RP, Tang E, Veizovic T, Sowniski P, et al.
Author(s): Englund U, Bjorklund A, Wictorin K, Lindvall O, Kokaia M
Author(s): Kopen GC, Prockop DJ, Phinney DG
Author(s): Chen J, Li Y, Chopp M
Author(s): Li Y, Chopp M, Chen J, Wang L, Gautam SC, et al.
Author(s): Woodbury D, Schwarz EJ, Prockop DJ, Black IB
Author(s): Muñoz-Elias G, Marcus AJ, Coyne TM, Woodbury D, Black IB
Author(s): Borlongan CV, Hadman M, Sanberg CD, Sanberg PR
Author(s): Eglitis MA, Mezey E
Author(s): Li Y, Chen J, Wang L, Lu M, Chopp M
Author(s): Chen J, Sanberg PR, Li Y, Wang L, Lu M, et al.
Author(s): Hess DC, Hill WD, Martin-Studdard A, Carroll J, Brailer J, et al.
Author(s): Willing AE, Lixian J, Milliken M, Poulos S, Zigova T, et al.
Author(s): Chen J, Zhang ZG, Li Y, Wang L, Xu YX, et al.
Author(s): Riess P, Zhang C, Saatman KE, Laurer HL, Longhi LG, et al.
Author(s): Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, et al.
Author(s): Peled A, Kollet O, Ponomaryov T, Petit I, Franitza S, et al.
Author(s): Yamaguchi J, Kusano KF, Masuo O, Kawamoto A, Silver M, et al.
Author(s): Reyes M, Dudek A, Jahagirdar B, Koodie L, Marker PH, et al.
Author(s): Rajantie I, Ilmonen M, Alminaite A, Ozerdem U, Alitalo K, et al.
Author(s): Mahmood A, Lu D, Chopp M
Author(s): Suárez-Monteagudo C, Hernández-Ramírez P, Alvarez-González L, García-Maeso I, de la Cuétara-Bernal K, et al.
Author(s): Borlongan CV
Author(s): Feuerstein GZ, Zaleska MM, Krams M, Wang X, Day M, et al.
Author(s): Keene CD, Ortiz-Gonzalez XR, Jiang YH, Largaespada DA, Verfaillie CM, et al.
Author(s): Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, et al.
Author(s): Jorgensen C, Djouad F, Apparailly F, Noël D
Author(s): Le Blanc K, Tammik L, Sundberg B, Haynesworth SE, Ringdén O
Author(s): Aggarwal S, Pittenger MF
Author(s): Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC
Author(s): Le Blanc K, Rasmusson I, Sundberg B, Götherström C, Hassan M, et al.
Author(s): Reyes M, Verfaillie CM
Author(s): Ayata C, Ropper AH
Author(s): Brouns R, De Deyn PP
Author(s): Aoki T, Sumii T, Mori T, Wang XY, Lo EH
Author(s): Subramaniam S, Hill MD
Author(s): Chang CF, Lin SZ, Chiang YH, Morales M, Chou J, et al.
Author(s): Castillo J, Alvarez-Sabín J, Martínez-Vila E, Montaner J, Sobrino T, et al.
Author(s): Vila N, Castillo J, Dávalos A, Chamorro A
Author(s): Castillo J, Leira R
Author(s): Doyle KP, Simon RP, Stenzel-Poore MP
Author(s): Wang GJ, Deng HY, Maier CM, Sun GH, Yenari MA
Author(s): Tang Y, Xu H, Du X, Lit L, Walker W, et al.
Author(s): Carmeliet P
Author(s): Masuda H, Asahara T
Author(s): Shi Q, Rafii S, Wu MH, Wijelath ES, Yu C, et al.
Author(s): Bompais H, Chagraoui J, Canron X, Crisan M, Liu XH, et al.
Author(s): Pirro M, Schillaci G, Menecali C, Bagaglia F, Paltriccia R, et al.
Author(s): Umemura T, Soga J, Hidaka T, Takemoto H, Nakamura S, et al.
Author(s): Del Papa N, Quirici N, Soligo D, Scavullo C, Cortiana M, et al.
Author(s): Kuwana M, Okazaki Y, Yasuoka H, Kawakami Y, Ikeda Y
Author(s): Heiss C, Keymel S, Niesler U, Ziemann J, Kelm M, et al.
Author(s): Kondo T, Hayashi M, Takeshita K, Numaguchi Y, Kobayashi K, et al.
Author(s): Michaud SE, Dussault S, Haddad P, Groleau J, Rivard A
Author(s): Botta R, Gao E, Stassi G, Bonci D, Pelosi E, et al.
Author(s): Kawamoto A, Gwon HC, Iwaguro H, Yamaguchi JI, Uchida S, et al.
Author(s): Madeddu P, Emanueli C, Pelosi E, Salis MB, Cerio AM, et al.
Author(s): Erbs S, Linke A, Adams V, Lenk K, Thiele H, et al.
Author(s): Li ZQ, Zhang M, Jing YZ, Zhang WW, Liu Y, et al.
Author(s): Meluzín J, Janousek S, Mayer J, Groch L, Hornácek I, et al.
Author(s): Meluzín J, Mayer J, Groch L, Janousek S, Hornácek I, et al.
Author(s): Mocini D, Staibano M, Mele L, Giannantoni P, Menichella G, et al.
Author(s): Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, et al.
Author(s): Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, et al.
Author(s): Strauer BE, Brehm M, Zeus T, Bartsch T, Schannwell C, et al.
Author(s): Strauer BE, Brehm M, Zeus T, Köstering M, Hernandez A, et al.
Author(s): Numaguchi Y, Sone T, Okumura K, Ishii M, Morita Y, et al.
Author(s): Döbert N, Britten M, Assmus B, Berner U, Menzel C, et al.
Author(s): Lev EI, Kleiman NS, Birnbaum Y, Harris D, Korbling M, et al.
Author(s): Hristov M, Heussen N, Schober A, Weber C
Author(s): Dimmeler S, Zeiher AM, Schneider MD
Author(s): Higashi Y, Kimura M, Hara K, Noma K, Jitsuiki D, et al.
Author(s): Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, et al.
Author(s): Taguchi A, Matsuyama T, Moriwaki H, Hayashi T, Hayashida K, et al.
Author(s): Ghani U, Shuaib A, Salam A, Nasir A, Shuaib U, et al.
