A new library of 4(3H)- and 4,4'(3H,3H')-quinazolinones and 2-(5-alkyl-1,2,4-oxadiazol-3-yl)quinazolin-4(3H)-one obtained from diaminoglyoxime

Author(s): Moghimi A, Khanmiri RH, Omrani I, Shaabani A

Abstract

New and efficient approaches are developed for the synthesis of a series of 4(3H)- and 4,4′(3H,3H′)-quinazolinone derivatives and 2-(5-alkyl-1,2,4-oxadiazol-3-yl)quinazolin-4(3H)-one in good yields, via the reactions of diaminoglyoxime and anthranilic acid derivatives or methyl 2-aminobenzoate and acetic anhydride in acetic acid as the solvent under reflux conditions.

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