Author(s): Yadav AK, Dhakad P, Sharma GR
A new, environmentally benign two-step synthesis of 5H[1,3]-thiazolo[2,3-b]quinazoline-3,5-(2H)-dione and 5H-thiazolo[2,3-b]quinazolin-5-one derivatives has been accomplished stepwise. The substituted 2-aminobenzoic acid upon condensation with thiourea in 1-butyl-3-methylimidazolium bromide at moderate temperature under nitrogen atmosphere yielded 2-thioxo-1H-4-quinazolinones. The resulting intermediate 2-thioxo-1H-4-quinazolinones, when reacted with 2-chloroethanoic acid/2-chloropropanal underwent cyclization to yield the desired product in excellent yields.
Author(s): Xu Z, Zhang Y, Fu H, Zhong H, Hong K, et al.
Author(s): Moghimi A, Khanmiri RH, Omrani I, Shaabani A
Author(s): Mashraqui SH, Ghorpade SS, Tripathi S, Britto S
Author(s): Duan Y, Zhu XY, Ma JA, Zhou YG
Author(s): Motegi M, Nugroho AE, Hirasawa Y, Arai T, Hamid A, et al.
Author(s): Lu L, Zhang MM, Jiang H, Wang XS
Author(s): El-Azab AS, Eltahir KE
Author(s): Wang Z, Wang M, Yao X, Li Y, Tan J, et al.
Author(s): Ramesh G, Narender P, Venkateshwarlu G, Avinash BC, VenkataRao C, et al.
Author(s): Yadav MR, Grande F, Chouhan BS, Naik PP, Giridhar R, et al.