Analgesic and psychopharmacological effects of the gum resin of Boswellia serrata

Author(s): Menon MK, Kar A


The non–phenolic fraction obtained from the gurn resin of Boswellia serrata Roxb. was found to exhibit marked sedative and analgesic effects. The drug produced a reduction in the spontaneous motor activity and caused ptosis in rats. A significant analgesic effect was observed as evaluated by both the hot–wire and the mechanical pressure methods. These effect started within 30 minutes and lasted for about 2 hours. Nalorphine caused only an insignificant antagonism to the analgesic effect of the drug. The fraction potentiated the secobarbitone–induced hypnosis in rats. The secondary–conditioned response (SCR) was specifically blocked in the trained rats, whereas the conditioned–avoidance response (CAR) was not significantly affected.

Similar Articles

Recent trends in use of herbal and other natural products

Author(s): Kelly JP, Kaufman DW, Kelley K, Rosenberg L, Anderson TE, et al.

Interaction of Aqueous Extract of Pleurotus pulmonarius (Fr

Author(s): Badole SL, Patel NM, Thakurdesai PA, Bodhankar SL

Clinical profile of the novel sulphonylurea glimepiride

Author(s): Rosskamp R, Wernicke-Panten K, Draeger E

Determination of glimepiride in rat serum by RP-HPLC method

Author(s): Sujatha S, Sandhya Rani T, Veeresham C