Author(s): Menon MK, Kar A
The non–phenolic fraction obtained from the gurn resin of Boswellia serrata Roxb. was found to exhibit marked sedative and analgesic effects. The drug produced a reduction in the spontaneous motor activity and caused ptosis in rats. A significant analgesic effect was observed as evaluated by both the hot–wire and the mechanical pressure methods. These effect started within 30 minutes and lasted for about 2 hours. Nalorphine caused only an insignificant antagonism to the analgesic effect of the drug. The fraction potentiated the secobarbitone–induced hypnosis in rats. The secondary–conditioned response (SCR) was specifically blocked in the trained rats, whereas the conditioned–avoidance response (CAR) was not significantly affected.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/5573545
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