Antioxidant property of an ethanol extract of the stem of Opuntiaficus-indica var

Author(s): Lee JC, Kim HR, Kim J, Jang YS


An ethanol extract of the stem of Opuntia ficus-indica var. saboten (OFS) was assessed to determine the mechanism(s) of its antioxidant activity. The ethanol extract exhibited a concentration-dependent inhibition of linoleic acid oxidation in a thiocyanate assay system. In addition, the OFS extract showed dose-dependent free-radical scavenging activity, including DPPH radicals, superoxide anions (O(2)(*-)), and hydroxyl radicals (*OH), using different assay systems. The OFS ethanol extract was also found to be effective in protecting plasmid DNA against the strand breakage induced by hydroxyl radicals in a Fenton's reaction mixture. Furthermore, the extract showed significant (p < 0.01) dose-dependent protection of mouse splenocytes against glucose oxidase-mediated cytotoxicity. Finally, the OFS extract was characterized as containing a high amount of phenolics (180.3 mg/g), which might be the active compounds responsible for the antioxidant properties of the OFS extract.

Similar Articles

Antigenotoxic, antimutagenic and ROS scavenging activities of a Rhoeo discolor ethanolic crude extract

Author(s): Gonzalez-Avila MM, Arriaga-Alba M, Garza de la, Carmen HP, del Dominguez-Ortiz M, et al

Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringaoleifera

Author(s): Singh BN, Singh BR, Singh RL, Prakash D, Dhakarey R, et al.

Nitric oxide in arthritis

Author(s): Jang D, Murrell GA

In vivo assessment of DNA damage and protective effects of extracts from Miconia species using the comet assay and micronucleus test

Author(s): Serpeloni JM, Bisarro dos Reis M, Rodrigues J, Campaner dos Santos L, Vilegas W, et al.