Author(s): Luo CT, Mao SS, Liu FL, Yang MX, Chen H, et al.
Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-β-d-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(β-d-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(β-d-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(β-d-glucoside) (4), together with twenty-one known xanthones (5–25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORACFL assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where 1 is the most active compound and 13 is the least one. A preliminary structure–activity relationship is also discussed.
Graphical abstractFour new xanthones, together with 21 known xanthones have been isolated from Swertia mussotii. Antioxidant capacity of all compounds was evaluated by ORACFL assay.
Author(s): Yang H, Ding C, Duan Y, Liu J
Author(s): Yang YC
Author(s): Negi JS, Singh P, Rawat B
Author(s): Zhang JS, Wang XM, Dong XH, Yang HY, Li GP
Author(s): Shang J, Zhang GY, Yang CB, Chen Z
Author(s): Brahmachari G, Mondal S, Gangopadhyay A, Gorai D, Mukhopadhyay B, et al.
Author(s): Sun HF, Hu BL, Ding JY, Fan SF
Author(s): Sun HF, Ding JY
Author(s): Louh GN, Lannang AM, Mbazoa CD, Tangmouo JG, Komguem J, et al.
Author(s): Chin YW, Jung HA, Chai H, Keller WJ, Kinghorn AD
Author(s): Fouotsa H, Lannang AM, Mbazoa CD, Rasheed S, Marasini BP, et al.
Author(s): Jantan I, Saputri FC
Author(s): Zhang JS, Wang XM, Gao YT, Li GP
Author(s): Uvarani C, Chandraprakash K, Sankaran M, Ata A, Mohan PS
Author(s): Luo CT, Zheng HH, Mao SS, Yang MX, Luo C, et al.
Author(s): Chow CK, Hong CB
Author(s): IARC
