Author(s): Faturi CB,Leite JR,Alves PB,Canton AC,Teixeira-Silva F
Aromatherapy is the use of essential oils as an alternative treatment for medical purposes. Despite the lack of sufficient scientific proof, it is considered a holistic complementary therapy employed to enhance comfort and decrease distress. Citrus fragrances have been particularly used by aromatherapists for the treatment of anxiety symptoms. Based on this claim, the present study investigated the effects of Citrus sinensis (sweet orange) essential oil on Wistar, male rats evaluated in the elevated plus-maze followed by the light/dark paradigm. The animals were exposed to the orange aroma (100, 200 or 400 microl) for 5 min while in a Plexiglas chamber and were then immediately submitted to the behavioural tests. At all doses, C.sinensis oil demonstrated anxiolytic activity in at least one of the tests and, at the highest dose, it presented significant effects in both animal models, as indicated by increased exploration of the open arms of the elevated plus-maze (time: p=0.004; entries: p=0.044) and of the lit chamber of the light/dark paradigm (time: p=0.030). In order to discard the possibility that this outcome was due to non-specific effects of any odour exposure, the behavioural response to Melaleuca alternifolia essential oil was also evaluated, using the same animal models, but no anxiolytic effects were observed. These results suggest an acute anxiolytic activity of sweet orange essence, giving some scientific support to its use as a tranquilizer by aromatherapists.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/20211673
Author(s): Sayers J
Author(s): Barlow DH
Author(s): Reardon LE, Leen-Feldner EW, Hayward CA
Author(s): Hellión-Ibarrola MC, Ibarrola DA, Montalbetti Y, Kennedy ML, Heinichen O, et al.
Author(s): Andrews G, Sanderson K, Slade T, Issakidis C
Author(s): Lawless J
Author(s): De Sousa DP
Author(s): Shaw D, Annett JM, Doherty B, Leslie JC
Author(s): Almeida RN, Motta SC, Faturi CB, Catallani B, Leite JR
Author(s): Pultrini AM, Galindo LA, Costa M
Author(s): Takahashi M, Satou T, Ohashi M, Hayashi S, Sadamoto K, et al.
Author(s): Linck VM, da Silva AL, Figueiró M, Caramão EB, Moreno PR, et al.
Author(s): Höferl M, Krist S, Buchbauer G
Author(s): Hatano VY, Torricelli AS, Giassi AC, Coslope LA, Viana MB
Author(s): Gomes PB, Feitosa ML, Silva MI, Noronha EC, Moura BA, et al.
Author(s): Melo FH, Venâncio ET, de Sousa DP, de França Fonteles MM, de Vasconcelos SM, et al.
Author(s): Silva MI, de Aquino Neto MR, Teixeira Neto PF, Moura BA, do Amaral JF, et al.
Author(s): Costa CA, Kohn DO, de Lima VM, Gargano AC, Flório JC, et al.
Author(s): Goes TC,Antunes FD,Alves PB,Teixeira-Silva F
Author(s): Lima NG, De Sousa DP, Pimenta FC, Alves MF, De Souza FS, et al.