Chemical composition and antibacterial activity of essential oil from leaves, stems and flowers of Prangos ferulacea (L

Author(s): Akbari MT, Esmaeili A, Zarea AH, Saad N, Bagheri F


Essential oils from the leaves, stems and flowers of Prangos ferulacea (family Umbelliferae) growing in Esfahan, Iran, were obtained by hydrodistillation using a Clevenger-type apparatus and their chemical composition and antibacterial activity analysed by GC-MS. All the oils consisted mainly of oxygenated monoterpenes and a small percentage of sesquiterpene compounds. In the oil from the leaf, 10 components were identified, dominated by oxygenated monoterpenes. The three major constituents identified (representing 65.1% of the oil) were linalool (36.7%), caryophyllene oxide (16.3%) and α-pinene (12.1%). In the stem oil, 11 compounds were identified, with oxygenated monoterpenes again predominating. The two major constituents identified (representing 29.3% of the oil) were 1,8-cineole (19.0%) and α-pinene (10.3%). Of the 17 compounds found in the flower oil, the five main components identified (representing 74.1% of the oil) were oxygenated monoterpenes: linalool (19.0%), lavandulyl acetate (16.0%), 1,8-cineole (14.5%), α-pinene (12.4%) and geranyl isobutyrate (12.2%). The oils were tested against four Gram-positive or Gram-negative bacteria. Antibacterial activity was measured using a dilution method. It was found that oil from leaves, stems and flowers of P. ferulacea, and especially that of leaves, exhibited interesting antibacterial activity.

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