Author(s): Zhang XY, Li1 B, Zhou M, Yuan X, Zhang G
The bulb of Fritillaria ebeiensis var. purpurea G.D. Yu et P. Li (Liliaceae) are commercially available as the substitute for the principal Chinese traditional medicine "Beimu". This plant is easily cultivated, has high alkaloid content and conspicuous antitussive and expectorant effects. Seven C-nor-D-homo steroidal alkaloids (I-VII) were isolated from the bulb cultivated in Suizhou district, Hubei. I-IV have been identified as the known alkaloids peimine, peiminine, ebeinine and ebeinone on the basis of spectral data and by TLC and mixed mp comparison with authentic samples. The alkaloid VI, C27H43NO2, mp 186-188 degrees C, named ziebeimine, is a new alkaloid isolated from the title plant. The structure of VI has been established as 5 alpha, 14 alpha-cevanine-13, 17-dehydro-3 alpha, 6 beta-diol on the basis of its IR, 1H-NMR, 13C-NMR and mass spectra. The structure of alkaloids V and VII is still under investigation.
Referred From: https://pubmed.ncbi.nlm.nih.gov/2618704/
Author(s): Concha DM, Vogel H, Yunes R, Razmilic I, Bresciani L, et al.
Author(s): Rodriguez B, Zapata N, Medina P, Viñuela E
Author(s): Monsalvez M, Zapata N, Vargas M, Bittner M, Hernandez V
Author(s): Jansen BJM, Groot AD
Author(s): Jansen BJM, Groot AD
Author(s): Brown GD
Author(s): Osorio LM, Cortes M, Armstrong V, Bailen M, Coloma AG
Author(s): Fujita K, Kubo I
Author(s): Munoz O, Christen P, Cretton S, Barrero AF, Laraf A, et al.
Author(s): Pothacharoen PP, Settakorn J, Poompimol W, Caterson B, Kongtawelert P
Author(s): Jayasinghe L, Kumarihamy M, Jayarathna N, Udishani G, Bandara R, Et Al
Author(s): Kuchkova K, Aricu N, Dragalin P, Vlad P
Author(s): Harrigan GG, Ahmad A, Baj N, Glass TE, Guaatilaka A, et al.
Author(s): Akita H, Nozawa M, Mitsuda A, Ohsawa H
Author(s): Appel HH, Conolly JD, Overton KH, Bond R
Author(s): Maurs M, Azerad R,Corte M, Aranda G, Bertranne M, et al.
Author(s): Sierra JR, Lopez J, Cortes M
Author(s): Meselhy MR
Author(s): Pascol ID, Nascimento I, Lopes L
Author(s): Morais S, Teixeira A, Torres Z, Nunomura S, Kanashiro EY, et al.
Author(s): Tuleda LR, Barchiesi F, Bille J, Chryssanthou E, Estrella MC, et al.
Author(s): Favre B, Hofbauer B, Hildering K, Ryder NS
Author(s): Gutierrez M, Theoduloz C, Rodriguez J, Lolas M. Schmeda-Hirschmann G
Author(s): Lee Ch, Chim Yen G
Author(s): Himejima M, Kubo I
Author(s): Kang R, Helms R, Stout M, Jaber H, Chen Z, et al.
Author(s): Saleem M, Kim HJ, Ali MS, Lee YS
Author(s): Verdeguer M, Rellán DG, Boira H, Pérez E, Gandolfo S, et al.
