[Chemical studies of crude drugs (1)

Author(s): Kitagawa I, Yoshikawa M, Yoshihara M, Hayashi T, Taniyama T


During the studies on the chemical characterization of crude drug precession, the constituents of Ginseng Radix Rubra were investigated by comparing with those of Ginseng Radix. Panaxynol (4), ginsenosides Ro, Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, Rg2 (11), Rg3 (10a), and Rh1 (9) were identified as common constituents of both Ginseng, whereas panaxytriol (1), ginsenoside Rh2 (8), 20 (R)-ginsenoside Rh1 (9a), 20 (S)-ginsenoside Rg3 (10), and 20 (R)-ginsenoside Rg2 (11a) were elucidated as characteristic constituents of Ginseng Radix Rubra. It was also found that Ginseng Radix Rubra contained larger quantities of ginsenosides Rh1 (9), Rg3 (10a), and Rg2 (11) than Ginseng Radix. The less polar constituents of Ginseng Radix Rubra were shown to significantly differ from those of various samples of Ginseng Radix by means of the thin layer chromatographyprofile analysis.

Similar Articles

Interactions between traditional Chinese medicines and Western therapeutics

Author(s): Chan E, Tan M, Xin J, Sudarsanam S, Johnson DE

The Role of Coenzyme Q10 in Heart Failure

Author(s): Weant KA, Smith KM

The impact of coenzyme Q10 on systolic function in patients with chronic heart failure

Author(s): Sander S, Coleman CI, Patel AA, Kluger J, White CM

Studies on the constituents of Japanese and Chinese crude drugs

Author(s): Shibata S, Fujita M, Itokawa H, Tanaka O, Ishii T

Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng

Author(s): Chan RY, Chen WF, Dong A, Guo D, Wong MS

Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells

Author(s): Fei XF, Wang BX, Tashiro S, Li TJ, Ma JS, et al.

Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells

Author(s): Kim HS, Lee EH, Ko SR, Choi KJ, Park JH, et al.

Rh2 synergistically enhances paclitaxel or mitoxantrone in prostate cancer models

Author(s): Xie X, Eberding A, Madera C, Fazli L, Jia W, et al.

Liquid chromatographic determination of less polar ginsenosides in processed ginseng

Author(s): Kwon SW, Han SB, Park IH, Kim JM, Park MK, et al.

[Determination of ginsenoside Rd and its metabolites in rat urine by LC-MS]

Author(s): Yang L, Xu SJ, Zeng X, Liu YM, Deng SG, et al.

Determination of Ginsenoside Rh2 in Enzyme Conversion by HPLC

Author(s): Jiang L, Zhao S, Ya L, Li J