Chemistry, pharmacology and clinical properties of Sambucusebulus: A review

Author(s): Shokrzadeh M, SaeediSarvari SS


Sambucus ebulus is known as dwarf elder or elderberry. S. ebulus extracts are an important area in drug development with numerous pharmacological functions in the Middle East. However, their pharmacological functions have not been clearly studied. For a long time, S. ebulus has been prescribed in traditional medicines for the treatment of inflammatory reactions, such as hemorrhoid, bites and sore-throat. In addition, S. ebulus has recently been shown to have anti-inflammatory, antinociceptive, anti-cancer, anti-angiogenic and anti-oxidative activities. Ebulitin, ebulin 1, flavonoid, athocyanin and other components have been isolated from S. ebulus and identified as active ingredients of biological and pharmacological activities. Due to the easy collection of the plant and remarkable biological activities, this plant has become both food and medicine in the coastal area of Iran. This review presents comprehensive analyzed information on the botanical, chemical, toxicopharmacological and clinical aspects of S. ebulus.

Similar Articles

Angiogenesis: from plants to blood vessels

Author(s): Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN

Angiogenic effects of the extracts from Chinese herbs: Angelica and Chuanxiong

Author(s): Meng H, Guo J, Sun JY, Pei JM, Wang YM, et al.

Effects of ursolic acid on different steps of the angiogenic process

Author(s): Cárdenas C, Quesada AR, Medina MA

Ferulic acid augments angiogenesis via VEGF, PDGF and HIF-1 alpha

Author(s): Lin CM, Chiu JH, Wu IH, Wang BW, Pan CM, et al.

Wound healing potential of Sambucusebulus L

Author(s): Süntar IP, Akkol EK, Yalçin FN, Koca U, Keles H, et al.

Basic and therapeutic aspects of angiogenesis

Author(s): Potente M, Gerhardt H, Carmeliet P

Cutaneous wound healing

Author(s): Singer AJ, Clark RA

Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts

Author(s): Wang S, Zheng Z, Weng Y, Yu Y, Zhang D, et al.