Author(s): Mirakhur RK, Dundee JW
Atropine and glycopyrrolate (glycopyrronium bromide), a quaternary ammonium drug, were evaluated in volunteers following intramuscular administration with respect to effects on various end-organs with cholinergic innervation. Glycopyrrolate appears to be five to six times more potent than atropine in its antisialogogue effect and also exhibits a selective, though prolonged, effect on salivary secretion and sweat gland activity. It has minimal cardiovascular, ocular and central nervous system effects.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/7241426
Author(s): Berdai MA, Labib S, Chetouani K, Harandou M
Author(s): Joshi P, Wicks AC, Munshi SK
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Author(s): Moulton BC, Fryer AD
Author(s): Caksen H, Odabas D, Akbayram S, Cesur Y, Arslan S, et al.
Author(s): Laffargue F, Oudot C, Constanty A, Bedu A, Ketterer-Martinon S
Author(s): Mirakhur RK, Dundee JW
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Author(s): National Heart Lung and Blood Institute, National Asthma Education and Prevention Program
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