Author(s): Wang P, Li S, Ownby S, Zhang Z, Yuan W, et al.
Phytoecdysteroid glycosides (1-5) and a phenylpropanoid ester of sucrose (6) were isolated from the whole plant of Froelichia floridana, along with eight known compounds including three ecdysteroids (7-9), four flavonoids (10-13), and one phenolic compound (14). Structures were determined using a combination of spectroscopic techniques. Compounds 1, 2 and 6-14 were tested in vitro for their activity against human DNA topoisomerase I. Compound 13 (diosmetin) showed marginal inhibition against topoisomerase I with IC(50) of 130 microM in conjunction with low intercalation ability.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/19254799
Author(s): Salvador MJ, Ferreira EO, Mertens-Talcott SU, De Castro WV, Butterweck V, et al.
Author(s): Cai Y, Sun M, Corke H
Author(s): Li H, Deng Z, Liu R, Zhu H, Draves J, et al.
Author(s): Liu H, Cao J, Jiang W
Author(s): Souza JG, Tomei RR, Kanashiro A, Kabeya LM, Azzolini AECS, et al.
Author(s): Kumar G, Karthik L, Rao KV
Author(s): Ranju P, Kundlik G, Hitesh G, Thirumoorthy N
Author(s): Biella CA, Salvador MJ, Dias DA, Dias-Baruffi M, Crotti LSP
Author(s): Teixeira CGL, Piccoli A, Costa P, Soares L, Da Silva-Santos JE
Author(s): Freitas CS, Baggio CH, Da Silva-Santos JE, Rieck L, de Moraes Santos CA, et al.
Author(s): Sanoko R, Esperanza G, Pizza C, De Tommasi N
Author(s): Harbone JB
Author(s): Piccinelli AL, De Simone F, Passi S, Rastrelli L
Author(s): Cuendet M, Hostettman K, Potterat O, Dyatmko W
Author(s): Huang D, Ou B, Prior RL
Author(s): Ou B, Hampsch-Woodill M, Prior RL
Author(s): Salvador MJ, de Lourenço CC, Andreazza NL, Pascoal AC, Stefanello ME
Author(s): Ye M, Han J, Chen H, Zheng J, Guo D
Author(s): Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, et al.
Author(s): Pietta PG
Author(s): Rice-Evans CA, Miller NJ, Paganga G
Author(s): Soares SE
Author(s): Zocoler AMD, Sanches ACC, Albrecht I, Mello JCP
Author(s): Custodio L, Fernandes E, Escapa AL, Fajardo A, Aligue R, et al.
Author(s): Salvador MJ, Andreazza NL, Pascoal ACRF, Pereira PS, França SC, et al.
Author(s): Carneiro CS, Costa-Pinto FA, da Silva AP, Pinello KC, da Silva TC, et al.
Author(s): Rao YK, Geethangili M, Fang SH, Tzeng YM
Author(s): Choi HJ, Eun JS, Kim BG, Kim SY, Jeon H, et al.
Author(s): Zhou Y, Liu YE, Cao J, Zeng G, Shen C, et al.
