Flavonoids from Centaurea clementei

Author(s):  I Gonzalez Collado, FA Macias, GM Massanet, F Rodriguez Luis

Abstract

The present study was carried out on the aerial parts ofC. raphanina Sm. ssp. mixta (DC.) Runemark (Asteraceae),which is a commonly edible plant in Greece, on maturation
stage. Although the isolation procedure is the appropriateone for the isolation of sesquiterpene lactones, the analysisrevealed the presence of only one sesquiterpene lactone, namely cnicin, in small amounts. The main compounds were found to belong to polyphenols. The in vitro antifungal activ-ity of the isolated compounds was tested, using the micro-dilution method. Only cnicin has been proved to be active against all fungi tested with a fungicidal potential higher than miconazole

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