High Throughput Screening: The Discovery of Bioactive Substances

Author(s): Devlin JP

Abstract

Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.

Similar Articles

Medicinal plants in therapy

Author(s): Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z

Burger's medicinal chemistry and drug discovery

Author(s): James F, Kerwin Jr.

Antimalarial drug resistance

Author(s): White NJ

Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

Author(s): Dondorp A, Nosten F, Stepniewska K, Day N, White N; South East Asian Quinine Artesunate Malaria Trial (SEAQUAMAT) group

Artesunate versus quinine for severe falciparum malaria

Author(s): Woodrow CJ, Planche T, Krishna S

Artemisinins: activities and actions

Author(s): Haynes RK, Krishna S

Artemisone--a highly active antimalarial drug of the artemisinin class

Author(s): Haynes RK, Fugmann B, Stetter J, Rieckmann K, Heilmann HD, et al.

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

Author(s): Uhlemann AC, Cameron A, Eckstein-Ludwig U, Fischbarg J, Iserovich P, et al.

Identification of an antimalarial synthetic trioxolane drug development candidate

Author(s): Vennerstrom JL, Arbe-Barnes S, Brun R, Charman SA, Chiu FC, et al.

Synthetic studies towards halichondrins: synthesis of the C

Author(s): Aicher TD, Buszek KR, Fang FG, Forsyth CJ, Jung SH, et al.

Enabling high-throughput discovery

Author(s): Vaschetto M, Weissbrod T, Bodle D, Güner O