Author(s): Nakayama M, Suzuki K, Toda M, Okubo S, Hara Y, et al.
(-)Epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) (1-10 microM) inhibited the infectivity of both influenza A virus and influenza B virus in Madin-Darby canine kidney (MDCK) cells in vitro. Study by electron microscope revealed that EGCg and TF3 (1 mM) agglutinated influenza viruses as well as did antibody, and that they prevented the viruses from adsorbing to MDCK cells. EGCg and TF3 more weakly inhibited adsorption of the viruses to MDCK cells. EGCg and TF3 (1-16 microM) also inhibited haemagglutination by influenza viruses. These findings suggest that tea polyphenols bind to the haemagglutinin of influenza virus, inhibit its adsorption to MDCK cells, and thus block its infectivity.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/8215301
Author(s): Yamashita M, Tomozawa T, Kakuta M, Tokumitsu A, Nasu H, et al.
Author(s): Smee D, Huffman JH, Morrison AC, Barnard DL, Sidwell RW
Author(s): Nakayama M, Toda M, Okubo S, Hara Y, Shimamura T
Author(s): Mori S, Miyake S, Kobe T, Nakaya T, Fuller SD, et al.
Author(s): Kaihatsu K, Mori S, Matsumura H, Daidoji T, Kawakami C, et al.
Author(s): Sundararajan A, Ganapathy R, Huan L, Dunlap JR, Webby RJ, et al.
Author(s): Sekizawa H, Ikuta K, Mizuta K, Takechi S, Suzutani T
Author(s): Sokmen M, Angelova M, Krumova E, Pashova S, Ivancheva S, et al.
Author(s): Gaush CR, Smith TF
Author(s): Davis J, Murphy EA, McClellan JL, Carmichael MD, Gangemi JD
Author(s): Gazák R, Purchartová K, Marhol P, Zivná L, Sedmera P, et al.