Natural products active against African trypanosomes: a step towards new drugs

Author(s): Hoet S, Opperdoes F, Brun R, Quetin-Leclercq J


This review covers compounds with activity on African trypanosomes (mainly Trypanosoma brucei subsp.,T congolense and T vivax) isolated from natural sources and is organized according to the structure of the etabolites (alkaloids, phenolic derivatives, quinones, terpenes and other metabolites). The literature from he mid-1980s up to June 2003 is reviewed and 89 references are cited.

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