Author(s): Dessì A, Crisafulli M, Accossu S, Setzu V, Fanos V
Osteoarticular infections, although uncommon, represent a severe condition in neonates. Infections in newborns are largely of an acute nature, transmitted by hematogenous means. The most frequently observed etiological agents are: Staphylococcus aureus, Gram negative and group B Streptococcus spp. In the majority of cases the metaphyses of the long bone are the most commonly implicated sites, although infection may spread to the contiguous epiphysis and joint in neonates. Diagnosis of acute septic arthritis and osteomyelitis may be hindered, especially in neonates, due to the manifestation of less clear-cut characteristic symptoms and signs compared to in children. When osteomyelitis is suspected, imaging techniques used in association with blood and tissue cultures are the most reliable diagnostic tests. Antimicrobial treatment should be administered for 3-4 weeks, initially intravenously, later switching to oral medication. Surgery is indicated to drain acute abscesses or when no improvement is achieved following antibiotic treatment.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/19028615
Author(s): Ramalingam K, Amaechi BT, Ralph RH, Lee VA
Author(s): Fukushima T, Iwao H, Nakazima A, Miki M, Sakai T, et al.
Author(s): Rokadiya S, Malden NJ
Author(s): Santos FA, Bastos EM, Rodrigues PH, Uzeda M, Carvalho MAR, et al.
Author(s): Sreeja S, Babu PRS, Prathab AG
Author(s): Rams TE, Degener JE, van Winkelhoff AJ
Author(s): Cragg GM, Newman DJ, Snader KM
Author(s): Maekawa LE, Valera MC, Oliveira LD, Carvalho CA, Camargo CH, et al.
Author(s): Bonifácio BV, Silva PB, Ramos MA, Negri KM, Bauab TM, et al.
Author(s): Santos VR, Gomes RT, de Mesquita RA, de Moura MD, França EC, et al.
Author(s): Pereira EM, da Silva JL, Silva FF, De Luca MP, Ferreira EF, et al.
Author(s): Gomaa OM, Gaweesh AS
Author(s): Banskota AH, Tezuka Y, Kadota S
Author(s): Dornelas CA, Fechine-Jamacaru FV, Albuquerque IL, Magalhães HI, Dias TA, et al.
Author(s): Machado JL, Assunção AK, da Silva MC, Dos Reis AS, Costa GC, et al.
Author(s): de Oliveira PF, Leandro LF, Montanheiro G, Bastos JK, da Silva Filho AA, et al.
Author(s): Oliveira GA, Ferraz ER, Souza AO, Lourenço RA, Oliveira DP, et al.
Author(s): Righi AA, Alves TR, Negri G, Marques LM, Breyer H, et al.
Author(s): Teixeira EW, Negri G, Meira RM, Message D, Salatino A
Author(s): de Almeida EB, Cordeiro Cardoso J, Karla de Lima A, de Oliveira NL, de Pontes-Filho NT, et al.
Author(s): Sharaf S, Higazy A, Hebeish A
Author(s): Santos VR
Author(s): Park YK, Alencar SM, Aguiar CL
Author(s): Batista LL, Campesatto EA, Assis ML, Barbosa AP, Grillo LA, et al.
Author(s): Marcucci MC
Author(s): Gazzani G, Daglia M, Papetti A
Author(s): Santos VR, Pimenta FJ, Aguiar MC, do Carmo MA, Naves MD, et al.
Author(s): Samet N, Laurent C, Susarla SM, Samet-Rubinsteen N
Author(s): Jebahi S, Oudadesse H, Jardak N, Khayat I, Keskes H, et al.
Author(s): Rivadeneira J, Carina Audisio M, Boccaccini AR, Gorustovich AA
Author(s): Wei QW, Dong YM, Chen XF, Li YL, Miao GH
Author(s): Kaczmarek M, Jurczyk MU, Rubis B, Banaszak A, Kolecka A, et al.
Author(s): Andrade AL, Manzi D, Domingues RZ
Author(s): Alencar SM, Oldoni TL, Castro ML, Cabral IS, Costa-Neto CM, et al.
Author(s): Daugsch A, Moraes CS, Fort P, Park YK
Author(s): Trusheva B, Popova M, Bankova V, Simova S, Marcucci MC, et al.
Author(s): Miorin PL, Levy Junior NC, Custodio AR
Author(s): Ayres DC, Marcucci MC, Giorgio S
Author(s): Park YK, Koo MH, Abreu JA, Ikegaki M, Cury JA, et al.
Author(s): Leitão DP, Filho AA, Polizello AC, Bastos JK, Spadaro AC
Author(s): Ferreira SBS, Assis Dias BR, Obregón CS, Gomes CC, de Araujo Pereira RR et al.
Author(s): Topcuoglu N, Ozan F, Ozyurt M, Kulekci G
Author(s): Ramos DBM, Gomes FS, Napoleão TH, Paiva PMG, Silva MDC, et al.
Author(s): Bueno-Silva B, Alencar SM, Koo H, Ikegaki M, Silva GV, et al.
Author(s): Libério SA, Pereira AL, Araújo MJ, Dutra RP, Nascimento FR, et al.
Author(s): Dziedzic A, Kubina R, Wojtyczka RD, KabaÅ‚a-Dzik A, Tanasiewicz M, et al.
Author(s): Jorgensen JH, Swenson JM, Tenover FC, Barry A, Ferraro MJ, et al.
Author(s): Gajan EB, Shirmohammadi A, Aghazadeh M, et al.
Author(s): Pondei K, Fente BG, Oladapo O
Author(s): Song XL, Sun YY, Liu Y, Chen Q, Bi XX, et al.
Author(s): Poptani B, Sharaff M, Archana G, Parekh V
Author(s): Cao WB, Su D, Chen YM, Zheng YZ, Zhang FK, et al.
Author(s): Olczak-Kowalczyk D, Daszkiewicz M, Krasuska-Slawinska, Dembowska-Baginska B, Gozdowski D, et al.
Author(s): Allan I, Newman H, Wilson M
Author(s): Krishnan V, Lakshmi T