Author(s): Kensil CR
Naturally occurring triterpene glycosides (saponins) from Quillaja saponaria have considerable adjuvant activity. Adjuvant functions include stimulation of high levels of antibody to T-dependent and T-independent antigens, induction of mouse IgG1, IgG2b, and IgG2a isotypes, and induction of cytotoxic T lymphocyte responses. This article reviews responses due to specific saponins of saponin preparations, effect of formulation, structure/function studies, and use in different preclinical and clinical vaccine applications.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/8853958
Author(s): Kensil CR, Kammer R
Author(s): Kensil CR, Patel U, Lennick M, Marciani D
Author(s): Garçon N, Van Mechelen M
Author(s): Garçon N, Chomez P, Van Mechelen M
Author(s): Sun HX, Xie Y, Ye YP
Author(s): Ragupathi G, Gardner JR, Livingston PO, Gin DY
Author(s): Lee S, Nguyen MT
Author(s): Warshakoon HJ, Hood JD, Kimbrell MR, Malladi S, Wu WY, et al
Author(s): Dalsgaard K
Author(s): Campbell JB, Peerbaye YA
Author(s): Kenney JS, Hughes BW, Masada MP, Allison AC
Author(s): Song X, Hu S
Author(s): Borja GPC, Correia NNP, Silva VOD, Paraguai SED, Santos WR, et al.
Author(s): Kirk DD, Rempel R, Pinkhasov J, Walmsley AM
Author(s): Hu KF, Lövgren-Bengtsson K, Morein B
Author(s): Morein B, Hu KF, Abusugra I
Author(s): Kersten G, Hirschberg H
Author(s): Aguilar JC, Rodríguez EG
Author(s): Kensil CR, Wu JY, Anderson CA, Wheeler DA, Amsden J
Author(s): Katayama S, Oda K, Ohgitani T, Hirahara T, Shimizu Y
Author(s): Liu G, Anderson C, Scaltreto H, Barbon J, Kensil CR
Author(s): Marciani DJ, Kensil CR, Beltz GA, Hung CH, Cronier J, et al.
