Staphylococcus aureus biofilms: properties, regulation, and roles in human disease

Author(s): Archer NK, Mazaitis MJ, Costerton JW, Leid JG, Powers ME, et al.

Abstract

Increasing attention has been focused on understanding bacterial biofilms and this growth modality's relation to human disease. In this review we explore the genetic regulation and molecular components involved in biofilm formation and maturation in the context of the Gram-positive cocci, Staphylococcus aureus. In addition, we discuss diseases and host immune responses, along with current therapies associated with S. aureus biofilm infections and prevention strategies.

Similar Articles

Plant defense and antimicrobial peptides

Author(s): Castro MS, Fontes W

Bacteriocins

Author(s): Riley MA, Chavan MA

Pediocin PA-1, a wide-spectrum bacteriocin from lactic acid bacteria

Author(s): Rodríguez JM, Martínez MI, Kok J

Development of novel therapeutic drugs in humans from plant antimicrobial peptides

Author(s): da Rocha Pitta MG, da Rocha Pitta MG, Galdino SL

CAMP: a useful resource for research on antimicrobial peptides

Author(s): Thomas S, Karnik S, Barai RS, Jayaraman VK, Idicula-Thomas S

Advances in antimicrobial peptide immunobiology

Author(s): Yount NY, Bayer AS, Xiong YQ, Yeaman MR

Novel properties of antimicrobial peptides

Author(s): Kamysz W, Okroj M, Lukasiak J

Impact of LL-37 on anti-infective immunity

Author(s): Bowdish DM, Davidson DJ, Lau YE, Lee K, Scott MG, et al.

Cationic host defense (antimicrobial) peptides

Author(s): Brown KL, Hancock RE

Potential of immunomodulatory host defense peptides as novel anti-infectives

Author(s): Easton DM, Nijnik A, Mayer ML, Hancock RE

Antimicrobial peptides: general overview and clinical implications in human health and disease

Author(s): Guaní-Guerra E, Santos-Mendoza T, Lugo-Reyes SO, Terán LM

Actinopyga lecanora Hydrolysates as Natural Antibacterial Agents

Author(s): Ghanbari R, Ebrahimpour A, Abdul-Hamid A, Ismail A, Saari N

Antimicrobial and antistaphylococcal biofilm activity from the sea urchin Paracentrotus lividus

Author(s): Schillaci D, Arizza V, Parrinello N, Di Stefano V, Fanara S, et al.

beta-Thymosins, small acidic peptides with multiple functions

Author(s): Huff T, M&uller CS, Otto AM, Netzker R, Hannappel E

Antimicrobial peptides from human platelets

Author(s): Tang YQ, Yeaman MR, Selsted ME

ß-thymosins and hemocyte homeostasis in a crustacean

Author(s): Saelee N, Noonin C, Nupan B, Junkunlo K, Phongdara A, et al.

Direct inactivation of viruses by human granulocyte defensins

Author(s): Daher KA, Selsted ME, Lehrer RI

Quorum sensing and DNA release in bacterial biofilms

Author(s): Spoering AL, Gilmore MS

Evolving concepts in biofilm infections

Author(s): Hall-Stoodley L, Stoodley P

Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal

Author(s): Landini P, Antoniani D, Burgess JG, Nijland R

Membrane permeabilization by multivalent anti-microbial peptides

Author(s): Pieters RJ, Arnusch CJ, Breukink E