Structurally diversified products from the reactions of 2-aminobenzamides with 1,3-cyclohexanediones catalyzed by iodine

Author(s): Lu L, Zhang MM, Jiang H, Wang XS


Controlling the reaction temperature at 50 °C, 80 °C, and 110 °C, respectively, the iodine-catalyzed reaction of 2-aminobenzamides with 1,3-cyclohexanediones gave structurally diversified products. In the latter, it gave bis-quinazolin-4(3H)-ones unexpectedly, with 1,3-cyclohexanediones ring-opening.

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