Author(s): Aicher TD, Buszek KR, Fang FG, Forsyth CJ, Jung SH, et al.
An efficient synthesis of the C.27–C.38 segment of halichondrins is accomplished, using the Ireland-Claisen rearrangement, Ni(II)/Cr(II)-mediated coupling and Michael reactions as the key steps.
An efficient synthesis of the C.27–C.38 segment 12 of halichondrins is reported, using the Ireland-Claisen rearrangement, Ni(II)/Cr(II)-mediated coupling and Michael reactions as the key steps.
Author(s): Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z
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