:2010-2013

Author(s): Bagan, P., et al. “Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: A review of the literature.” Ann Thorac Surg. 82.6

Abstract

Background

Pulmonary epithelioid hemangioendothelioma is a rare vascular tumor of low-grade malignancy, the prognosis of which remains unpredictable. The purpose of this analysis based on 80 patients was to determine prognostic factors and to evaluate results of surgery.

Methods

We recorded data of 75 patients from reports published in the English and French literature using the terms “intravascular bronchoalveolar tumor” or “pulmonary epithelioid hemangioendothelioma” or a combination of both. We added to this database 5 more cases of pulmonary epithelioid hemangioendothelioma operated on in our thoracic surgery department from 1989 to 2005. Univariate and multivariate analyses of prognostic factors were performed using the log rank test and the Cox model. The factors we tested were age, sex, clinical symptoms, biologic and radiologic findings, and surgical treatment.

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