Author(s): Azimi H
Objective:In this paper, we reviewed plants being effective in treatment of BPH for the purpose of finding new sources of pharmaceutical agents.
Methods:All pertinent literature databases were searched. The search keywords were plant, herb, herbal therapy, phytotherapy, benign prostatic hyperplasia, BPH, and prostate. All of the human, animal and in vitro studies were evaluated.
Results:According to the studies, some of the substantial effective constituents of the plants in treatment of BPH are oenothein B, icaritin, xanthohumol, diarylheptanoid, 2,6,4'-trihydroxy-4-methoxybenzophenone, emodin, fatty acids, atraric acid, n-butylbenzene-sulfonamide, curbicin, theaflavin-3,30-digallate, penta-O-galloyl-b-D-glucose, lycopene, sinalbin, β-sitosterol, secoisolariciresinol diglucoside, genistein, apigenin, baicalein, and daidzein. Besides, Serenoa repens, Pygeum africanum, Curcubita pepo, and Urtica dioica as the most prevalent plants used to treat BPH. S. repens in human studies showed equivalent effectiveness to tamsulosin and in combination to U. dioica revealed equal effects to finastride with less side effects.
Conclusion:There are numerous plants that have beneficial influence on BPH although the mechanisms of action in some plants are not well understood yet. Active ingredients of some of these plants are known and can be used as lead components for development of new effective and safe drugs.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/22512478
Author(s): Giovannucci E
Author(s): Giovannucci E
Author(s): Le Marchand L,Hankin JH, Kolonel LN, Wilkens LR
Author(s): Stacewicz-Sapuntzakis M, Bowen PE
Author(s): Mohanty NK,Saxena S, Singh UP, Goyal NK, Arora RP
Author(s): Van Poppel H,Tombal B
Author(s): Madersbacher S, Berger I, Ponholzer A, Marszalek M
Author(s): Kim HS, Bowen P, Chen L, Duncan C, Ghosh L, et al.
Author(s): Obermüller-Jevic UC,Olano-Martin E, Corbacho AM, Eiserich JP, van der Vliet A, et al.
Author(s): Herzog A, Siler U, Spitzer V, Seifert N, Denelavas A, et al.
Author(s): Schwarz S,Obermüller-Jevic UC, Hellmis E, Koch W, Jacobi G, et al.
Author(s): Dewell A, Weidner G, Sumner MD, Chi CS, Ornish D
Author(s): Park E,Stacewicz-Sapuntzakis M, Sharifi R, Wu Z, Freeman VL, et al.
Author(s): Parsons JK, Newman VA, Mohler JL, Pierce JP, Flatt S, et al.
Author(s): Carmody JF,Olendzki BC, Merriam PA, Liu Q, Qiao Y, et al.
Author(s): vanBreemen RB,Sharifi R, Viana M, Pajkovic N, Zhu D, et al.
Author(s): Barber NJ, Barber J
Author(s): Hadley CW, Miller EC, Schwartz SJ, Clinton SK
Author(s): Richelle M,Bortlik K, Liardet S, Hager C, Lambelet P, et al.
Author(s): Burri BJ, Chapman MH, Neidlinger TR, Seo JS, Ishida BK
Author(s): Diwadkar-Navsariwala V, Novotny JA, Gustin DM, Sosman JA, Rodvold KA, et al.
Author(s): Canene-Adams K,Lindshield BL, Wang S, Jeffery EH, Clinton SK, et al.
Author(s): Limpens J,Schröder FH, de Ridder CM, Bolder CA, Wildhagen MF, et al.
Author(s): Yang CM
Author(s): Konijeti R, Henning S, Moro A, Sheikh A, Elashoff D, et al.
Author(s): Venkateswaran V,Fleshner NE, Sugar LM, Klotz LH
Author(s): Mucci LA,Tamimi R, Lagiou P, Trichopoulou A, Benetou V, et al.
Author(s): Liu X
Author(s): Chan JM, Weinberg V, Magbanua MJ, Sosa E, Simko J, et al.
Author(s): Siler U, Herzog A, Spitzer V, Seifert N, Denelavas A, et al.
Author(s): Talvas J,Caris-Veyrat C, Guy L, Rambeau M, Lyan B, et al.
Author(s): Qiu X, Yuan Y, Vaishnav A, Tessel MA, Nonn L, et al.
Author(s): SoaresNda C,Teodoro AJ, Oliveira FL, Santos CA, Takiya CM, et al.
Author(s): Teodoro AJ, Oliveira FL, Martins NB, Maia Gde A, Martucci RB, et al.
Author(s): Oborna I
Author(s): Kirsh VA,Mayne ST, Peters U, Chatterjee N, Leitzmann MF, et al.
Author(s): Peters U
Author(s): Kristal AR, Till C, Platz EA, Song X, King IB, et al.
Author(s): Ilic D, Forbes KM, Hassed C
Author(s): Bunker CH, McDonald AC, Evans RW, de la Rosa N, Boumosleh JM, et al.
Author(s): Schröder FH,Roobol MJ, Boevé ER, de Mutsert R, Zuijdgeest-van Leeuwen SD, et al.
Author(s): Barber NJ
Author(s): Edinger MS, Koff WJ
Author(s): Bowen P, Chen L, Stacewicz-Sapuntzakis M, Duncan C, Sharifi R, et al.
Author(s): Morgia G, Russo GI, Voce S, Palmieri F, Gentile M, et al.
Author(s): Morgia G
Author(s): Morgia G,Mucciardi G, Galì A, Madonia M, Marchese F, et al.
Author(s): Blume-Peytavi U