Author(s): Liu H, Liu JY, Wu X, Zhang JT
Fatty acid synthase (FAS), the sole mammalian enzyme capable of de novo fatty acid synthesis, is highly expressed in most human carcinomas. FAS is associated with poor prognosis in breast and prostate cancer, is elaborated into the blood of cancer patients, and its inhibition is selectively cytotoxic to human cancer cells. Thus, FAS and fatty acid metabolism in cancer has become a focus for the potential diagnosis and treatment of cancer. (Cancer Res 2006; 66(12): 5977-80)
Referred From: https://aacrjournals.org/cancerres/article/66/12/5977/525703/Fatty-Acid-Synthase-and-Cancer-New-Application-of
Author(s): Kusakabe T, Maeda M, Hoshino H, Sugino T, Watanabe K, et al.
Author(s): Sul HS, Wang D
Author(s): Kuhajda FP
Author(s): Mashima T, Seimiya H, Tsuruo T
Author(s): Maekawa H, Ito T, Orita H, Sato K, Wada R
Author(s): Maekawa H, Ito T, Kushida T, Orita H, Sakurada M, et al.
Author(s): Ghouri YA, Mian I, Blechacz B
Author(s): Bergguist A, von Seth E
Author(s): Zhang JW, Chu YM, Lan ZM, Tang XL, Chen YT, et al.
Author(s): Kiriyama M, Ebata T, Aoba T, Kaneoka Y, Arai T, et al.
Author(s): Sakata J, Wakai T, Matsuda Y, Ohashi T, Hirose Y, et al.
Author(s): Kim HJ, Kim CY, Hur YH, Koh YS, Kim JC, et al.
Author(s): Kwon HJ, Kim SG, Chun JM, Lee WK, Hwang YJ
Author(s): Wang J, Wang X, Xie S, Yan Z, Li Z, et al.
Author(s): Miyamoto M, Ojima h, Iwasaki M, Shimizu H, Kokubu A, et al.
Author(s): Zheng J, Zhu YM
Author(s): Chang YT, Chang MC, Huang KW, Tung CC, Hsu C, et al.
Author(s): Pattanathien P, Khuntikeo N, Promthet S, Kamsa-Ard S
Author(s): Lad N, Kooby DA
Author(s): Yang H, Zhou J, Wei X, Wang F, Zhao H, et al.
Author(s): Im JH, Seong J, Lee IJ, Park JS, Yoon DS, et al.
Author(s): Hoehn RS, Wima K, Ertel AE, Meier A, Ahmad SA, et al.
Author(s): Coleman DT, Bigelow R, Cardelli JA
