Author(s): Parikh RB, Cronin AM, Kozono DE, Oxnard GR, Mak RH, et al.
Although palliative chemotherapy is the standard of care for patients with diagnoses of stage IV non-small cell lung cancer (NSCLC), patients with a small metastatic burden, “oligometastatic” disease, may benefit from more aggressive local therapy.Methods and Materials
We identified 186 patients (26% of stage IV patients) prospectively enrolled in our institutional database from 2002 to 2012 with oligometastatic disease, which we defined as 5 or fewer distant metastatic lesions at diagnosis. Univariate and multivariable Cox proportional hazards models were used to identify patient and disease factors associated with improved survival. Using propensity score methods, we investigated the effect of definitive local therapy to the primary tumor on overall survival.
Author(s): Quint LE, Tummala S, Brisson LJ, Francis IR, Krupnick AS, et al.
Author(s): Bohman L, Bassett L, Gold R, Voet R
Author(s): Amichetti M, Perani B, Boi S
Author(s): Lee SH, Park JM, Kook SH, Han BK, Moon WK
Author(s): Vergier B, Trojani M, De Mascarel I, Coindre JM, Le Treut A
Author(s): Mirrielees JA, Kapur JH, Szalkucki LM, Harter JM, Salkowski LR, et al.
Author(s): Dansin E, Carnot A, Servent V, Daussay D, Robin YM, et al.
Author(s): Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, et al.
Author(s): Nielsen M, Ørnvold K, Andersen Ja, HenriksenFw, Kristensen Pb, et al.
Author(s): Vizcaino I, Torregrosa A, Higueras V, Morote V, Cremades A, et al.
Author(s): Huang HC, Hang JF, Wu MH, Chou TY, Chiu CH
Author(s): Babu KS, Roberts F, Bryden F, McCafferty A, Downer P, et al.
Author(s): Maounis N, Chorti M, Legaki S, Ellina E, Emmanouilidou A, et al.
Author(s): Park SY, Kim BH, Kim JH, Lee S, Kang GH
Author(s): Turner BM, Cagle PT, Sainz IM, Fukuoka J, Shen SS, et al.
Author(s): Zhu B, Dalal S, Kamp DW, Lin X
Author(s): Rusthoven KE, Hammerman SF, Kavanagh BD, Birtwhistle MJ, Stares M, et al.
Author(s): Yano T, Okamoto T, Haro A, Fukuyama S, Yoshida T, et al.
Author(s): Yano T, Haro A, Yoshida T, Morodomi Y, Ito K, et al.
Author(s): Ashworth AB, Senan S, Palma DA, Riquet M, Ahn YC, et al.
Author(s): Yoon MY, Song CS, Seo MH, Kim MJ, Oh TY, et al.
Author(s): Kato T, Seto T, Nishio M, Goto K, Atagi S, et al.