Author(s): Zuckerman D, Seliem R, Hochberg E
Intravascular lymphoma (IVL) is a rare subtype of extranodal diffuse large B-cell lymphoma with a distinct presentation. Anatomically the disease is characterized by the proliferation of clonal lymphocytes within small vessels with relative sparing of the surrounding tissue. The clinical symptoms of the disease are dependent on the specific organ involvement, which most often includes the central nervous system and skin. Because of the various modes of presentation and the rarity of IVL, the diagnosis is often made postmortem. The diagnosis is almost exclusively made by surgical biopsy of a suspected site of involvement. Advances in imaging and immunohistochemistry have led to increasing antemortem diagnosis of this lymphoma. Although some patients with this disease may be curable with aggressive therapy, further research into novel treatment strategies is needed to improve outcome. Some potential insights into future therapies may be drawn from the small amount of basic science literature relevant to this entity. This review provides a concise, up-to-date summary of IVL.
Referred From: https://academic.oup.com/oncolo/article/11/5/496/6397086
Author(s): Shankland KR, Armitage JO, Hancock BW
Author(s): Yamada T, Iwao N, Kasamatsu H, Mori H
Author(s): Frey NV, Svoboda J, Andreadis C, Tsai DE, Schuster SJ, et al.
Author(s): Garavaglia E, Taccagni G, Montoli S, Panacci N, Ponzoni M, et al.
Author(s): Vang R, Medeiros LJ, Ha CS, Deavers M
Author(s): Berthold D, Ghielmini M
Author(s): Kosari F, Daneshbod Y, Parwaresch R, Krams M, Wacker HH
Author(s): Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, et al.
Author(s): Sur M, Ross C, Moens F, Daya D
Author(s): Yamada N, Uchida R, Fuchida S, Okano A, Okamoto M, et al.
Author(s): Lannoo L, Smets S, Steenkiste E, Delforge M, Moerman P, et al.
Author(s): Yamamoto T, Morita K, Iriyama N, Wakui K, Hiroi A, et al.
Author(s): Xia Y, Wang Y, Jiang Y, Yu W, Li Y, et al.
Author(s): Shigematsu Y, Matsuura M, Nishimura N, Tsuyama N, Takeuchi K, et al.
Author(s): Signorelli M, Maneo A, Cammarota S, Isimbaldi G, Garcia Parra R, et al.
Author(s): Anderson T, Chabner BA, Young RC, Berard CW, Garvin AJ, et al.
Author(s): Weingertner AS, Hamid D, Roedlich MN, Baldauf JJ
Author(s): Park SB, Lee YH, Song MJ, Cho HC, Lee MS, et al.
Author(s): Ansell SM
Author(s): Onyiuke I, Kirby AB, McCarthy S
Author(s): Murase T, Yamaguchi M, Suzuki R, Okamoto M, Sato Y, et al.
Author(s): Ponzoni M, Ferreri AJ, Campo E, Facchetti F, Mazzucchelli L, et al.
Author(s): Sehn LH, Berry B, Chhanabhai M, Fitzgerald C, Gill K, et al.